Russian Journal of Pediatric SurgeryRussian Journal of Pediatric SurgeryДетская хирургия1560-95102412-0677Eco-Vector60110.55308/1560-9510-2022-26-6-334-342ReviewsОБЗОРЫVenous thromboembolitic complications in children and adults with permanent venous access (literature review)Венозные тромбоэмболические осложнения у детей и взрослых с постоянным венозным доступом (обзор литературы)https://orcid.org/0000-0002-5113-9569CherkashinM. A.ЧеркашинМ. А.
Russian Federation

Mikhail А. Cherkashin, Deputy Chief Medical Officer, Surgeon

191144, St. Petersburg

Черкашин Михаил Александрович, заместитель главного врача по медицинской части, врач-хирург

191144, Санкт-Петербург

mc@ldc.ruhttps://orcid.org/0000-0002-4429-5723AlexandrovS. V.АлександровС. В.
Russian Federation

191144, St. Petersburg

191144, Санкт-Петербург

https://orcid.org/0000-0002-0757-4862BolshakovaT. V.БольшаковаТ. В.
Russian Federation

191144, St. Petersburg

191144, Санкт-Петербург

https://orcid.org/0000-0001-7337-2495NikolaevA. A.НиколаевА. А.
Russian Federation

191144, St. Petersburg

191144, Санкт-Петербург

https://orcid.org/0000-0003-3293-0061BoykoK. F.БойкоК. Ф.
Russian Federation

191144, St. Petersburg

191144, Санкт-Петербург

https://orcid.org/0000-0001-9772-4387BerezinaN. A.БерезинаН. А.
Russian Federation

191144, St. Petersburg

191144, Санкт-Петербург

Medical and Diagnostic Center of the International Institute of Biological Systems named after Sergey BerezinООО «Лечебно-диагностический центр международного института биологических систем имени Сергея Березина»2912202226633434208022023080220232022https://jps-nmp.ru/jour/article/view/601

Introduction. Over the past decades, permanent venous access devices, in particular port systems and peripherally implanted central catheters, has been increasingly introduced in adult and pediatric oncology. As far as central catheters and permanent access devices are foreign bodies in basic veins, quite naturally that they are one more risk factor for thrombosis.Material and methods. The authors searched literature data ( in Russian and English) for the period up to May 3, 2022 using public databases (Embase, Medline/PubMed, Researchgate, medrxiv.org, RSCI/eLibrary). The following keywords were used for the search: “port-system”, “peripherally implanted central catheter”, “totally implanted vascular access device”, “venous thromboembolism”, “VTE”, “venous thromboembolic complications”, “VTEC”, “catheter dysfunction”, “device malfunction”. Available preprints, articles with “in press” or “online first” status, and clinical cases were also included in the analysis.Conclusion. This review discusses prevention, diagnostics and treatment of venous thromboembolic complications in cancer patients using similar implantable devices. In patients with catheter-associated thromboses, of practical interest are various diagnostic and curative algorithms, recommendations on the choice of vascular access, medicamentous therapy as well as variants of surgical intervention.

Введение. На протяжении последних десятилетий во взрослой и детской онкологии всё шире внедряется использование устройств постоянного венозного доступа, в частности порт-систем и периферически имплантируемых центральных катетеров. Вследствие того, что центральные катетеры и устройства постоянного доступа являются инородными телами в магистральных венах, их наличие вполне закономерно является отдельным самостоятельным фактором риска тромбообразования.Материал и методы. Выполнен поиск литературы на русском и английском языках за период до 3 мая 2022 г. с использованием общедоступных баз данных (Embase, PubMed/Medline, Research gate, medrxiv.org, eLibrary/РИНЦ). Поиск выполнялся по ключевым словам «порт-система», «port-system», «periphera llyimplanted central catheter», «PICC» «total lyimplanted vascular raccess device», «venous thromboembolism», «VTE», «венозные тромбоэмболические осложнения», «ВТЭО», «дисфункция катетера», «devicemal function». В анализ были включены в том числе доступные препринты, статьи со статусом «в печати» или «online first», а также клинические случаи.Заключение. В данном обзоре рассматриваются вопросы профилактики, диагностики и лечения венозных тромбоэмболических осложнений у онкологических пациентов с подобными имплантируемыми устройствами. Практический интерес представляют различные алгоритмы диагностики и лечения и конкретные рекомендации по выбору сосудистого доступа, лекарственной терапии и подходам к хирургическому лечению катетер-ассоциированных тромбозов.

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