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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Pediatric Surgery</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Pediatric Surgery</journal-title><trans-title-group xml:lang="ru"><trans-title>Детская хирургия</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1560-9510</issn><issn publication-format="electronic">2412-0677</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">705</article-id><article-id pub-id-type="doi">10.17816/ps705</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Case reports</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Клинические случаи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Vaccum-therapy for treating a wound of difficult anatomic location in a 17-year old boy with systemic arthritis</article-title><trans-title-group xml:lang="ru"><trans-title>Использование вакуум-терапии в лечении раны сложной анатомической локализации у юноши 17 лет с системным артритом</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8563-6002</contrib-id><contrib-id contrib-id-type="spin">5709-3352</contrib-id><name-alternatives><name xml:lang="en"><surname>Dyakonova</surname><given-names>Elena Yu.</given-names></name><name xml:lang="ru"><surname>Дьяконова</surname><given-names>Елена Юрьевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine)</p></bio><bio xml:lang="ru"><p>доктор медицинских наук</p></bio><email>rytella@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2029-7820</contrib-id><contrib-id contrib-id-type="spin">1220-4593</contrib-id><name-alternatives><name xml:lang="en"><surname>Gusev</surname><given-names>Aleksey A.</given-names></name><name xml:lang="ru"><surname>Гусев</surname><given-names>Алексей Андреевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine), Assoc. Professor</p></bio><bio xml:lang="ru"><p>кандидат медицинских наук, доц.</p></bio><email>drgusev@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5900-1812</contrib-id><contrib-id contrib-id-type="spin">7699-2398</contrib-id><name-alternatives><name xml:lang="en"><surname>Bekin</surname><given-names>Aleksandr S.</given-names></name><name xml:lang="ru"><surname>Бекин</surname><given-names>Александр Сергеевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD</p></bio><email>aleksandr_bekin@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0764-1287</contrib-id><contrib-id contrib-id-type="spin">4890-8742</contrib-id><name-alternatives><name xml:lang="en"><surname>Yatsyk</surname><given-names>Sergey P.</given-names></name><name xml:lang="ru"><surname>Яцык</surname><given-names>Сергей Павлович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine), Professor, Corresponding Member of the Russian Academy of Sciences</p></bio><bio xml:lang="ru"><p>доктор медицинских наук, профессор, чл.-кор РАН</p></bio><email>yatsyk@nczd.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3436-7201</contrib-id><name-alternatives><name xml:lang="en"><surname>Tishkin</surname><given-names>German V.</given-names></name><name xml:lang="ru"><surname>Тишкин</surname><given-names>Герман Васильевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>lem19051917@gmail.com</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">National Medical Research Center for Children's Health</institution></aff><aff><institution xml:lang="ru">Национальный медицинский исследовательский центр здоровья детей</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Lomonosov Moscow State University</institution></aff><aff><institution xml:lang="ru">Московский государственный университет имени М.В. Ломоносова</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2024-08-12" publication-format="electronic"><day>12</day><month>08</month><year>2024</year></pub-date><pub-date date-type="pub" iso-8601-date="2024-09-09" publication-format="electronic"><day>09</day><month>09</month><year>2024</year></pub-date><volume>28</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>377</fpage><lpage>383</lpage><history><date date-type="received" iso-8601-date="2023-07-26"><day>26</day><month>07</month><year>2023</year></date><date date-type="accepted" iso-8601-date="2024-07-09"><day>09</day><month>07</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Dyakonova E.Y., Gusev A.A., Bekin A.S., Yatsyk S.P., Tishkin G.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, Дьяконова Е.Ю., Гусев А.А., Бекин А.С., Яцык С.П., Тишкин Г.В.</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Dyakonova E.Y., Gusev A.A., Bekin A.S., Yatsyk S.P., Tishkin G.V.</copyright-holder><copyright-holder xml:lang="ru">Дьяконова Е.Ю., Гусев А.А., Бекин А.С., Яцык С.П., Тишкин Г.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2025-09-09"/></permissions><self-uri xlink:href="https://jps-nmp.ru/jour/article/view/705">https://jps-nmp.ru/jour/article/view/705</self-uri><abstract xml:lang="en"><p><bold><italic>BACKGROUND</italic></bold><bold><italic>:</italic></bold> Vacuum therapy (VAC<sup>©</sup> Therapy, NPWT) is an effective method for treating wounds. Its principle is the following: a wound is covered with an airtight dressing, and negative pressure (50–125 mm Hg) is applied. Vacuum therapy is recommended for treating complex wounds.</p> <p><bold><italic>CLINICAL CASE DESCRIPTION: </italic></bold>In 2017, a patient, born in 2005, was diagnosed with “Juvenile arthritis with systemic onset, activity grade 2–1, X-ray stage 3, functional class 2”. Since then, he has been treated with immunosuppressants and corticosteroids. On November 9, 2022, edema, hyperemia, and hyperthermia of the medial half of the right gluteal region developed under immunosuppressive therapy. On November 11, 2022, necrotic discharge from the wound in the right gluteal region was noted. Diagnosis “Necrosis of subcutaneous fat of the right buttock spreading to the scrotum root” was put. On November 16, 2022, MRI was performed — a picture of widespread edema of fatty tissue to the right, in pararectal and gluteal regions with purulent content was revealed. The patient was transferred to the surgical department. Surgical debridement was performed under general anesthesia, and apparatus Suprasorb CNP P1 with intermittent negative pressure was put. On postoperative day 9, a stable positive effect was achieved in the form of wound healing with a tendency to secondary intention. During the wound revision on December 2, 2022, wound edges were clean; on December 16, 2022, the wound had a skin defect about 5×7 cm and no granulation in the wound depth. The wound was sutured. At the control examination on February 23, 2023, complete wound healing was seen.</p> <p><bold><italic>CONCLUSION</italic></bold><bold><italic>:</italic></bold> Vacuum therapy is an effective tool for managing complex wounds in pediatric surgery which leads to positive outcomes. At the same time, such outcomes largely depend on the whole set of measures, including adequate surgical debridement, careful monitoring and appropriate antibiotic therapy. Comorbidities also play their role in the disease process.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Обоснование</bold><bold>.</bold> Использование вакуум-терапии (VAC<sup>©</sup> Therapy, NPWT) хорошо зарекомендовало себя в лечении ран. В основе метода лежит воздействие на рану отрицательного давления (50–125 мм рт. ст.) через герметическую повязку. Вакуум-терапию рекомендуется использовать для лечения сложных ран.</p> <p><bold>Описание клинического случая.</bold> Пациенту 2005 года рождения в 2017 году поставлен диагноз «Юношеский артрит с системным началом, активность 2–1 степени, рентгенологическая стадия 3, функциональный класс 2». С 2017 года пациент получал терапию иммунодепрессантами и глюкокортикоидами. На фоне терапии 09.11.2022 развился отёк, гиперемия, гипертермия медиальной половины правой ягодичной области. С 14.11.2022 отмечалось некротическое отделяемое из раны в области правой ягодичной области. Поставлен диагноз «Некроз подкожной жировой клетчатки правой ягодицы с распространением к корню мошонки». В ходе магнитно-резонансной томографии (16.11.2022) выявлена картина распространённого отёка жировой клетчатки промежности справа, параректальной и ягодичной области с гнойным содержимым. Пациент переведён в хирургическое отделение. Под общей анестезией проведена хирургическая обработка раны и наложен аппарат интермиттирующего отрицательного давления Suprasorb CNP P1. На 9 послеоперационные сутки на фоне проводимой терапии достигнут стойкий положительный эффект в виде заживления раны с тенденцией ко вторичному заживлению. Ревизии раны: 02.12.2022 — края раны чистые; 16.12.2022 — рана представлена кожным дефектом размерами около 5×7 см с отсутствием грануляций в глубине раны. Рана ушита. На контрольном осмотре 23.02.2023 отмечается полное заживление.</p> <p><bold>Заключение.</bold> Вакуум-терапия эффективна для лечения сложных ран в детской хирургии и позволяет добиться положительного результата. Однако результат в значительной степени зависит от сопутствующей патологии и от всего комплекса мер, включая адекватную хирургическую обработку раны, тщательный мониторинг и соответствующую антибактериальную терапию.</p></trans-abstract><kwd-group xml:lang="en"><kwd>vacuum therapy</kwd><kwd>wound healing</kwd><kwd>bandages</kwd><kwd>immunosuppressive agents</kwd><kwd>phlegmon</kwd><kwd>adiponecrosis</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>вакуум-терапия</kwd><kwd>лечение ран</kwd><kwd>повязки</kwd><kwd>иммунодепрессанты</kwd><kwd>флегмона</kwd><kwd>адипонекроз</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Davydov JA, Larichev AB. 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