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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Pediatric Surgery</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Pediatric Surgery</journal-title><trans-title-group xml:lang="ru"><trans-title>Детская хирургия</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1560-9510</issn><issn publication-format="electronic">2412-0677</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">766</article-id><article-id pub-id-type="doi">10.17816/ps766</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Lectures</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Лекции</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Semi-elemental mixtures in the practice of a pediatric surgeon</article-title><trans-title-group xml:lang="ru"><trans-title>Полуэлементные смеси в практике детского хирурга</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8018-3366</contrib-id><contrib-id contrib-id-type="spin">7319-9906</contrib-id><name-alternatives><name xml:lang="en"><surname>Erpuleva</surname><given-names>Julia V.</given-names></name><name xml:lang="ru"><surname>Ерпулева</surname><given-names>Юлия Владимировна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine), Professor</p></bio><bio xml:lang="ru"><p>доктор медицинских наук, профессор</p></bio><email>erpulevaYuV@rmapo.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Russian Medical Academy of Continuous Professional Education</institution></aff><aff><institution xml:lang="ru">Российская медицинская академия непрерывного профессионального образования</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2024-08-07" publication-format="electronic"><day>07</day><month>08</month><year>2024</year></pub-date><pub-date date-type="pub" iso-8601-date="2024-09-09" publication-format="electronic"><day>09</day><month>09</month><year>2024</year></pub-date><volume>28</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>372</fpage><lpage>376</lpage><history><date date-type="received" iso-8601-date="2023-11-20"><day>20</day><month>11</month><year>2023</year></date><date date-type="accepted" iso-8601-date="2024-07-14"><day>14</day><month>07</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Erpuleva J.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, Ерпулева Ю.В.</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Erpuleva J.V.</copyright-holder><copyright-holder xml:lang="ru">Ерпулева Ю.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2025-09-09"/></permissions><self-uri xlink:href="https://jps-nmp.ru/jour/article/view/766">https://jps-nmp.ru/jour/article/view/766</self-uri><abstract xml:lang="en"><p>Since the first days of life nutrition is a necessary component of child's harmonious development. A particularly acute problem of child’s feeding is faced by physicians, if the child underwent any gastrointestinal surgery. Numerous studies have shown that malnutrition affects 50% of hospitalized children and 25–70% of seriously ill children. Natural nutrition is a real challenge for children in critical conditions. Currently, enteral nutrition is considered to be a preferred modality in pediatric patients with surgical pathology. A significant development of enteric formula industry over the past few years has put this type of nutrition at the forefront in helping operated children. Specialized mixtures for enteral nutrition which contain split protein or amino acid fragments gain an advantage over whole-protein mixtures. The lecture highlights main approaches to the prescription of enteral nutrition for children at the early postoperative and post-traumatic period.</p></abstract><trans-abstract xml:lang="ru"><p>Питание с первых дней жизни является необходимым компонентом гармоничного развития ребёнка. Особенно остро с проблемой кормления ребёнка сталкиваются лечащие врачи при операциях на желудочно-кишечном тракте. Многочисленные исследования показали, что от недоедания страдают 50% госпитализированных детей и 25–70% тяжелобольных детей. Существуют сложности проведения питания естественным путем у детей в критических состояниях. В наши дни энтеральное питание рассматривается предпочтительным методом лечения детей с хирургической патологией. Значительное развитие индустрии энтеральных смесей в течение последних нескольких лет поставило этот вид питания во главу помощи оперированным детям. Специализированные смеси для энтерального питания, в составе которых содержится расщеплённый белок, или фрагменты аминокислот, получили преимущество перед цельнобелковыми смесями. В лекции освещены основные подходы к назначению энтерального питания детям в раннем послеоперационном и посттравматическом периоде.</p></trans-abstract><kwd-group xml:lang="en"><kwd>enteral nutrition</kwd><kwd>operated children</kwd><kwd>hydrolyzed protein</kwd><kwd>hydrolyzed mixtures</kwd><kwd>whole protein mixtures</kwd><kwd>early postoperative period</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>энтеральное питание</kwd><kwd>оперированные дети</kwd><kwd>гидролизованный белок</kwd><kwd>гидролизованные смеси</kwd><kwd>цельнобелковые смеси</kwd><kwd>ранний послеоперационный период</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Erpulyova YV. Enteral nutrition for children: Indications, provision, means. Practical guide for doctors. Saint Petersburg: Eko-Vektor; 2022. (In Russ.)</mixed-citation><mixed-citation xml:lang="ru">Ерпулева Ю.В. Энтеральное питание детей: показания, обеспечение, средства. Практическое руководство для врачей. Санкт-Петербург: Эко-Вектор, 2022.</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">Selivanova AV. The hormone metabolic alterations in patients in critical state. Russ Clin Lab Diagnostic. 2012;(11):13–17. EDN: PUHJSP</mixed-citation><mixed-citation xml:lang="ru">Селиванова А.В. Гормонально-метаболические изменения у больных, находящихся в критическом состоянии // Клиническая лабораторная диагностика. 2012. № 11. С. 13–17. EDN: PUHJSP</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">Hanan I, Mervat M, Yasmin G. Peptide-based formula versus standard-based polymeric formula for critically ill children: Is it superior for patients’ tolerance? Arch Med Sci. 2020;16(3):592–596. doi: 10.5114/aoms.2020.94157</mixed-citation><mixed-citation xml:lang="ru">Hanan I., Mervat M., Yasmin G. Peptide-based formula versus standard-based polymeric formula for critically ill children: Is it superior for patients’ tolerance? // Arch Med Sci. 2020. Vol. 16, N 3. P. 592–596. doi: 10.5114/aoms.2020.94157</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><citation-alternatives><mixed-citation xml:lang="en">Liu MY, Tang HC, Hu SH, Chang SJ. Peptide-based enteral formula improves tolerance and clinical outcomes in abdominal surgery patients relative to a whole protein enteral formula. World J Gastroint Surg. 2016;8(10):700. doi: 10.4240/wjgs.v8.i10.700</mixed-citation><mixed-citation xml:lang="ru">Liu M.Y., Tang H.C., Hu S.H., Chang S.J. Peptide-based enteral formula improves tolerance and clinical outcomes in abdominal surgery patients relative to a whole protein enteral formula // World J Gastroint Surg. 2016. Vol. 8, N 10. P. 700. doi: 10.4240/wjgs.v8.i10.700</mixed-citation></citation-alternatives></ref><ref id="B5"><label>5.</label><citation-alternatives><mixed-citation xml:lang="en">Vidigal MV, Leite HP, Nogueira PC. Factors associated with peptide-based formula prescription in a pediatric intensive care unit. J Pediatr Gastroenterol Nutr. 2012;54(5):620–623. doi: 10.1097/MPG.0b013e31824a0149</mixed-citation><mixed-citation xml:lang="ru">Vidigal M.V., Leite H.P., Nogueira P.C. Factors associated with peptide-based formula prescription in a pediatric intensive care unit // J Pediatr Gastroenterol Nutr. 2012. Vol. 54, N 5. P. 620–623. doi: 10.1097/MPG.0b013e31824a0149</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><citation-alternatives><mixed-citation xml:lang="en">Tiengou LE, Gloro R, Pouzoulet J, et al. Semi-elemental formula or polymeric formula: Is there a better choice for enteral nutrition in acute pancreatitis? Randomized comparative study. J Parenter Enteral Nutr. 2006;30(1):1–5. doi: 10.1177/014860710603000101</mixed-citation><mixed-citation xml:lang="ru">Tiengou L.E., Gloro R., Pouzoulet J., et al. Semi-elemental formula or polymeric formula: Is there a better choice for enteral nutrition in acute pancreatitis? Randomized comparative study // J Parenter Enteral Nutr. 2006. Vol. 30, N 1. P. 1–5. doi: 10.1177/014860710603000101</mixed-citation></citation-alternatives></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">Bengmark S. Nutrition of the critically III: A 21st century perspective. Nutrients. 2013;5(1):162–207. doi: 10.3390/nu5010162</mixed-citation><mixed-citation xml:lang="ru">Bengmark S. Nutrition of the critically III: A 21st century perspective // Nutrients. 2013. Vol. 5, N 1. P. 162–207. doi: 10.3390/nu5010162</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><citation-alternatives><mixed-citation xml:lang="en">Nespoli L, Coppola S, Gianotti L. The role of the enteral route and the composition of feeds in the nutritional support of malnourished surgical patients. Nutrients. 2012;4(9):1230–1236. doi: 10.3390/nu4091230</mixed-citation><mixed-citation xml:lang="ru">Nespoli L., Coppola S., Gianotti L. The role of the enteral route and the composition of feeds in the nutritional support of malnourished surgical patients // Nutrients. 2012. Vol. 4, N 9. P. 1230–1236. doi: 10.3390/nu4091230</mixed-citation></citation-alternatives></ref><ref id="B9"><label>9.</label><citation-alternatives><mixed-citation xml:lang="en">Hur H, Kim SG, Shim JH, et al. Effect of early oral feeding after gastric cancer surgery: A result of randomized clinical trial. Surgery. 2011;149(4):561–568. doi: 10.1016/j.surg.2010.10.003</mixed-citation><mixed-citation xml:lang="ru">Hur H., Kim S.G., Shim J.H., et al. Effect of early oral feeding after gastric cancer surgery: A result of randomized clinical trial // Surgery. 2011. Vol. 149, N 4. P. 561–568. doi: 10.1016/j.surg.2010.10.003</mixed-citation></citation-alternatives></ref><ref id="B10"><label>10.</label><citation-alternatives><mixed-citation xml:lang="en">Doig GS, Simpson F, Sweetman EA, et al. Early parenteral nutrition in critically ill patients with short-term relative contraindications to early enteral nutrition: A randomized controlled trial. JAMA. 2013;309(20):2130–2138. doi: 10.1001/jama.2013.5124</mixed-citation><mixed-citation xml:lang="ru">Doig G.S., Simpson F., Sweetman E.A., et al. Early parenteral nutrition in critically ill patients with short-term relative contraindications to early enteral nutrition: A randomized controlled trial // JAMA. 2013. Vol. 309, N 20. P. 2130–2138. doi: 10.1001/jama.2013.5124</mixed-citation></citation-alternatives></ref><ref id="B11"><label>11.</label><citation-alternatives><mixed-citation xml:lang="en">Reignier J, Boisramé-Helms J, Brisard L, et al. Enteral versus parenteral early nutrition in ventilated adults with shock: A randomised, controlled, multicentre, open-label, parallel-group study (NUTRIREA-2). Lancet. 2018;391(10116):133–143. doi: 10.1016/S0140-6736(17)32146-3</mixed-citation><mixed-citation xml:lang="ru">Reignier J., Boisramé-Helms J., Brisard L., et al. Enteral versus parenteral early nutrition in ventilated adults with shock: A randomised, controlled, multicentre, open-label, parallel-group study (NUTRIREA-2) // Lancet. 2018. Vol. 391, N 10116. P. 133–143. doi: 10.1016/S0140-6736(17)32146-3</mixed-citation></citation-alternatives></ref><ref id="B12"><label>12.</label><citation-alternatives><mixed-citation xml:lang="en">Mehta NM, Skillman HE, Irving SY, et al Guidelines for the provision and assessment of nutrition support therapyin the pediatric critically ill patient: Society of critical care medicine and American society for parenteral and enteral nutrition. J Parenteral Enteral Nutrition. 2017;41(5):706–742. doi: 10.1177/0148607117711387</mixed-citation><mixed-citation xml:lang="ru">Mehta N.M., Skillman H.E., Irving S.Y., et al. Guidelines for the provision and assessment of nutrition support therapyin the pediatric critically ill patient: Society of critical care medicine and American society for parenteral and enteral nutrition // J Parenter Enteral Nutr. 2017. Vol. 41, N 5. P. 706–742. doi: 10.1177/0148607117711387</mixed-citation></citation-alternatives></ref><ref id="B13"><label>13.</label><citation-alternatives><mixed-citation xml:lang="en">Jotterand Chaparro C, Laure Depeyre J, Longchamp D, et al. How much protein and energy are needed to equilibrate nitrogen and energy balances in ventilated critically ill children? Clin Nutr. 2016;35(2):460–467. doi: 10.1016/j.clnu.2015.03.015</mixed-citation><mixed-citation xml:lang="ru">Chaparro J.C., Depeyre L.J., Longchamp D., et al. How much protein and energy are needed to equilibrate nitrogen and energy balances in ventilated critically ill children? // Clin Nutr. 2016. Vol. 35, N 2. P. 460–467. doi: 10.1016/j.clnu.2015.03.015</mixed-citation></citation-alternatives></ref><ref id="B14"><label>14.</label><citation-alternatives><mixed-citation xml:lang="en">Mehta NM, Bechard LJ, Zurakowski D, et al. Adequate enteral proteinintake is inversely associated with 60-D mortality in critically ill children: A multicenter, prospective, cohort study. Am J Clin Nutr. 2015;102(1):199–206. doi: 10.3945/ajcn.114.104893</mixed-citation><mixed-citation xml:lang="ru">Mehta N.M., Bechard L.J., Zurakowski D., et al. Adequate enteral proteinintake is inversely associated with 60-D mortality in critically ill children: A multicenter, prospective, cohort study // Am J Clin Nutr. 2015. Vol. 102, N 1. P. 199–206. doi: 10.3945/ajcn.114.104893</mixed-citation></citation-alternatives></ref><ref id="B15"><label>15.</label><citation-alternatives><mixed-citation xml:lang="en">Lekmanov AU, Erpuleva JV. Earlier enteral nutrition in critical conditions. Alexander Saltanov Intensive Care Herald. 2012;(3):53–55. (In Russ.) EDN: RDNTRP</mixed-citation><mixed-citation xml:lang="ru">Лекманов А.У., Ерпулева Ю.В. Ранее энтеральное питание при критических состояниях // Вестник интенсивной терапии. 2012. № 3. С. 53–55. EDN: RDNTRP</mixed-citation></citation-alternatives></ref><ref id="B16"><label>16.</label><citation-alternatives><mixed-citation xml:lang="en">Wong JJ, Han WM, Sultana R, et al. Nutrition delivery affects in pediatric ARDS. J Parenter Enteral Nutr. 2017;41(6):1007–1013. doi: 10.1177/0148607116637937</mixed-citation><mixed-citation xml:lang="ru">Wong J.J., Han W.M., Sultana R., et al. Nutrition delivery affects in pediatric ARDS // J Parenter Enteral Nutr. 2017. Vol. 41, N 6. P. 1007–1013. doi: 10.1177/0148607116637937</mixed-citation></citation-alternatives></ref><ref id="B17"><label>17.</label><citation-alternatives><mixed-citation xml:lang="en">Mikhailov TA, Kuhn EM, Manzi J, et al. Early enteral nutrition is associated with lower mortality in critically ill children. J Parenter Enteral Nutr. 2014;38(4):459–466. doi: 10.1177/0148607113517903</mixed-citation><mixed-citation xml:lang="ru">Mikhailov T.A., Kuhn E.M., Manzi J., et al. Early enteral nutrition is associated with lower mortality in critically ill children // J Parenter Enteral Nutr. 2014. Vol. 38, N 4. P. 459–466. doi: 10.1177/0148607113517903</mixed-citation></citation-alternatives></ref><ref id="B18"><label>18.</label><citation-alternatives><mixed-citation xml:lang="en">Manaf AZ, Kassim N, Hamzaid NH, Razali NH. Delivery of enteral nutrition for critically ill children. Nutr Diet. 2013;70(2):120–125. doi: 10.1111/1747-0080.12007</mixed-citation><mixed-citation xml:lang="ru">Manaf A.Z., Kassim N., Hamzaid N.H., Razali N.H. Delivery of enteral nutrition for critically ill children // Nutr Diet. 2013. Vol. 70, N 2. P. 120–125. doi: 10.1111/1747-0080.12007</mixed-citation></citation-alternatives></ref><ref id="B19"><label>19.</label><citation-alternatives><mixed-citation xml:lang="en">Mikhailov TA, Gertz SJ, Kuhn EM, et al. Early enteral nutrition is associated with signifcantly lower hospital charges in critically ill children. J Parenter Enter Nutr. 2018;42(5):920–925. doi: 10.1002/jpen.1025</mixed-citation><mixed-citation xml:lang="ru">Mikhailov T.A., Gertz S.J., Kuhn E.M., et al. Early enteral nutrition is associated with signifcantly lower hospital charges in critically ill children // J Parenter Enter Nutr. 2018. Vol. 42, N 5. P. 920–925. doi: 10.1002/jpen.1025</mixed-citation></citation-alternatives></ref><ref id="B20"><label>20.</label><citation-alternatives><mixed-citation xml:lang="en">Mehta NM. Feeding the gut during critical illness: It is about time. J Parenter Enteral Nutr. 2014;38(4):410–414. doi: 10.1177/0148607114522489</mixed-citation><mixed-citation xml:lang="ru">Mehta N.M. Feeding the gut during critical illness: It is about time // J Parenter Enteral Nutr. 2014. Vol. 38, N 4. P. 410–414. doi: 10.1177/0148607114522489</mixed-citation></citation-alternatives></ref></ref-list></back></article>
