2025 will a year of the 100^th anniversary of Saint Petersburg State Paediatric Medical University and a year of the 120^th anniversary of the clinical hospital. The article presents a register of surgeries which were performed in 1925 in the surgical clinic of the University. The articles reviews nosological structure of surgical patients, surgical procedures and anesthesia techniques used one hundred years ago. In the article, one can also find brief historical biographical notes about surgeons who were at the origins of the department and clinic of pediatric surgery of Saint Petersburg State Medical University: N.E. Berg, V.N. Katin-Yartsev, M.A. Toporkova, V.D. Sokolov, V.L. Magsky, A.I. Savshinsky and many others. The role of outstanding orthopedic traumatologist Prof. Roman R. Vreden, who founded the department and headed the surgical clinic of the University (then the Institute of Maternal and Infant Health) from 1925 to 1934 is underlined separately. Dr. Nikolai E. Berg, one of the founders of paediatric surgery, worked at the clinic and subsequently at the department from 1905 to 1949, including the war years and the Leningrad siege. Little information has been found on functioning of the surgical clinic in 1905–1925. There is a lot of work ahead with archives so as to study the history of the clinic and department of paediatric surgery in Saint-Petersburg State Paediatric Medical University.