LIVER BIOPSY IN CHILDRENS WITH CHRONIC LIVER PATHOLOGIES. CLINICAL OBSERVATIONS



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Abstract

Chronic liver diseases in children are characterized by a progressive course and lead to fibrotic changes in the organ up to cirrhotic transformation. Therapy effectiveness and patient’s quality of life depend on timely verified diagnosis and stage of the process. Morphological examination of hepatobiopsies remains a key issue in the diagnostics of histopathological changes in the liver; however, biopsy sampling is associated with a risk of complications and does not exclude insufficiently informative biopsies. This article discusses three clinical cases of patients in whom a personalized choice of the way of biopsy sampling allowed to avoid life-threatening complications and to obtain the most informative biopsy material.

About the authors

P. V. Khrolenko

National Medical Research Center of Children’s Health

Author for correspondence.
Email: polinakhrolenko@gmail.com
ORCID iD: 0000-0001-9814-6275
Россия

E. Yu. D'yakonova

National Medical Research Center of Children’s Health

Email: noemail@neicon.ru
ORCID iD: 0000-0002-8563-6002
Россия

A. N. Surkov

National Medical Research Center of Children’s Health; Pirogov Russian National Research Medical University

Email: noemail@neicon.ru
ORCID iD: 0000-0002-3697-4283
Россия

I. V. Dvoryakovsky

National Medical Research Center of Children’s Health

Email: noemail@neicon.ru
Россия

K. A. Kulikov

National Medical Research Center of Children’s Health

Email: noemail@neicon.ru
ORCID iD: 0000-0002-1107-8693
Россия

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