Modern approaches to the diagnostics and potentials of endoscopic treatment of esophageal stenoses in children



Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Introduction. Esophageal stenosis in childhood is quite a common disease characterized by different etiology, specific clinical picture, wide range of differential diseases and a variety of approaches to its treatment.

Material and methods. The review analyzes scientific literature presented in such search engines as Medline, PubMed, Cochrane Library, eLibrary, 20 years deep. The most significant works of the last century were included too. Keywords were used for search.

Results. There were selected 60 literary sources which included the description of modern concepts of etiopathogenesis, classification, diagnostic and curative techniques for the treatment of esophageal stenosis in children. A particular attention is paid to the safety and effectiveness of minimally invasive endoscopic interventions (bougienage, balloon dilation) as well as to the topical application of Mitomycin C in the treatment of esophageal stenosis in children.

Conclusion. Innovative endoscopic technologies applied for the restoration of the esophageal lumen seem to be promising, effective and safe. In the overwhelming majority of cases, they allow to reduce surgical aggression and avoid complex reconstructive surgeries.

About the authors

A. O. Merkulova

Clinical and Research Institute of Emergency Pediatric Surgery and Trauma

Author for correspondence.
Email: anast.merkulova@gmail.com
ORCID iD: 0000-0001-8623-0947

Anastasia О. Merkulova, MD, endoscopist at department of endoscopy

Moscow, 19180

Россия

A. Yu. Kharitonova

Clinical and Research Institute of Emergency Pediatric Surgery and Trauma

Email: fake@neicon.ru
ORCID iD: 0000-0001-6218-3605

Moscow, 19180

Россия

O. V. Karaseva

Clinical and Research Institute of Emergency Pediatric Surgery and Trauma;
National Medical Research Center of Children’s Health

Email: fake@neicon.ru
ORCID iD: 0000-0001-9418-4418

Moscow, 19180,

Moscow, 119296

Россия

A. A. Shavrov

Pirogov Russian National Research Medical University;
Morozovskaya Municipal Children’s Hospital

Email: fake@neicon.ru
ORCID iD: 0000-0003-3666-2674

Moscow, 117997,

Moscow, 119049

Россия

References

  1. Nihoul-Fekete C., De Backer A., Lortat-Jacob S., Pellerin D. Congenital esophageal stenosis, a review of 20 cases. Pediatr Surg Int. 1987; 2: 86–92.
  2. Romeo E., Foschia F., De Angelis P., et al. Endoscopic management of congenital esophageal stenosis. J Pediatr Surg. 2011; 46(5): 838–41.
  3. Dall’Oglio L., Caldaro T., Foschia F., Faraci S., Federici di Abriola G., Rea F., Romeo E., Torroni F., Angelino G., De Angelis P. Endoscopic management of esophageal stenosis in children: New and traditional treatments. World J Gastrointest Endosc. 2016; 8(4): 212–9.
  4. Saleem M.M. Acquired oesophageal strictures in children: emphasis on the use of string-guided dilatations. Singapore Med J. 2009 Jan; 50(1): 82-6.
  5. Terui K., Saito T., Mitsunaga T., Nakata M., Yoshida H. Endoscopic management for congenital esophageal stenosis: A systematic review. World J Gastrointest Endosc. 2015 Mar 16; 7(3): 183-91.
  6. Amae S., Nio M., Kamiyama T., Ishii T., Yoshida S., Hayashi Y., et al. Clinical characteristics and management of congenital esophageal stenosis: a report on 14 cases. J Pediatr Surg. 2003; 38(4): 565-70.
  7. Takamizawa S., Tsugawa C., Mouri N., Satoh S., Kanegawa K., Nishijima E., Muraji T. Congenital esophageal stenosis: Therapeutic strategy based on etiology. J Pediatr Surg. 2002 Feb; 37(2): 197-201.
  8. Dominguez R., Zarabi M., Oh K.S., Bender T.M., Girdany B.R. Congenital oesophageal stenosis. Clin Radiol. 1985 May; 36(3): 263-6.
  9. Ishida M., Tsuchida Y., Saito S., Tsunoda A. Congenital esophageal stenosis due to tracheobronchial remnants. J Pediatr Surg. 1969; 4(3): 339–45
  10. Nishina T., Tsuchida Y., Saito S. Congenital esophageal stenosis due to tracheobronchial remnants and its associated anomalies. J Pediatr Surg. 1981 Apr; 16(2): 190-3.
  11. Kawahara H., Imura K., Yagi M., Kubota A. Clinical characteristics of congenital esophageal stenosis distal to associated esophageal atresia. Surgery. 2001 Jan; 129(1): 29-38.
  12. Nemolato S., De Hertogh G., Van Eyken P., Faa G., Geboes K. Oesophageal tracheobronchial remnants. Gastroenterol Clin Biol. 2008 Aug-Sep; 32(8-9): 779-81.
  13. Jones D.W., Kunisaki S.M., Teitelbaum D.H., Spigland N.A., Coran AG. Congenital esophageal stenosis: the differential diagnosis and management. Pediatr Surg Int. 2010 May; 26(5): 547-51.
  14. Takayanagi K., Ii K., Komi N. Congenital esophageal stenosis with lack of the submucosa. J Pediatr Surg. 1975 Jun; 10(3): 425-6.
  15. McNally P.R., Lemon J.C., Goff J.S., Freeman S.R. Congenital esophageal stenosis presenting as noncardiac, esophageal chest pain. Dig Dis Sci. 1993 Feb; 38(2): 369-73.
  16. Yoo H.J., Kim W.S., Cheon J.E., Yoo S.Y., Park K.W., Jung S.E., Shin S.M., Kim I.O., Yeon K.M. Congenital esophageal stenosis associated with esophageal atresia/tracheoesophageal fistula: clinical and radiologic features. Pediatr Radiol. 2010 Aug; 40(8): 1353-9.
  17. Разумовский А.Ю., Алхасов А.Б., Гандуров С.Г. Пептические стенозы пищевода у детей. Детская хирургия. 2005; 2: 39-41.
  18. Pieczarkowski S., Woynarowski M., Landowski P., Wilk R, Daukszewicz A., Toporowska-Kowalska E., Albrecht P., Ignys I., Czkwianianc E., Jarocka-Cyrta E., Korczowski B. Endoscopic therapy of oesophageal strictures in children - a multicentre study. Prz Gastroenterol. 2016; 11(3): 194-9.
  19. Королёв М.П., Гольбиц С.В., Иванов А.П., Комиссаров М.И. Эндоскопическое лечение детей со стенозами пищевода различной этиологии. Вестник хирургии. 2012; 2: 52-7.
  20. Said M., Mekki M., Golli M., et al. Balloon dilatation of anastomoticstrictures secondary to surgical repair of oesophageal atresia. Br J Radiol. 2003; 76: 26-31.
  21. Parolini F., Leva E., Morandi A., Macchini F., Gentilino V., Di Cesare A., Torricelli M. Anastomotic strictures and endoscopic dilatations following esophageal atresia repair. Pediatr Surg Int. 2013 Jun; 29(6): 601-5.
  22. Zhao R., Li K., Shen C., Zheng S. The outcome of conservative treatment for anastomotic leakage after surgical repair of esophageal atresia. J Pediatr Surg 2011; 46(12): 2274–8.
  23. Murphy S.G., Yazbeck S., Russo P. Isolated congenital esophageal stenosis. J Pediatr Surg. 1995 Aug; 30(8): 1238-41.
  24. Achildi O., Grewal H. Congenital anomalies of the esophagus. Otolaryngol Clin North Am. 2007 Feb; 40(1): 219-44.
  25. Prasse J.E., Kikano G.E. An overview of pediatric dysphagia. Clin Pediatr (Phila). 2009 Apr; 48(3): 247-51.
  26. Hurtado C.W., Furuta G.T., Kramer R.E. Etiology of esophageal food impactions in children. J Pediatr Gastroenterol Nutr. 2011 Jan; 52(1): 43-6.
  27. Savino F., Tarasco V., Viola S., Locatelli E., Sorrenti M., Barabino A. Congenital esophageal stenosis diagnosed in an infant at 9 month of age. Ital J Pediatr. 2015 Oct 6; 41:72.
  28. Michaud L., Coutenier F., Podevin G., Bonnard A., Becmeur F., Khen-Dunlop N., Auber F., Maurel A., Gelas T., Dassonville M., Borderon C., Dabadie A., Weil D., Piolat C., Breton A., Djeddi D., Morali A., Bastiani F., Lamireau T., Gottrand F. Characteristics and management of congenital esophageal stenosis: findings from a multicenter study. Orphanet J Rare Dis. 2013 Dec 1; 8: 186.
  29. Quiros J.A., Hirose S., Patino M., Lee H. Esophageal tracheobronchial remnant, endoscopic ultrasound diagnosis, and surgical management. J Pediatr Gastroenterol Nutr. 2013 Mar; 56(3): e14.
  30. Lew R.J., Kochman ML. A review of endoscopic methods of esophageal dilation. J Clin Gastroenterol. 2002 Aug; 35(2): 117-26.
  31. Lan L.C., Wong K.K., Lin S.C., Sprigg A., Clarke S., Johnson P.R., Tam P.K. Endoscopic balloon dilatation of esophageal strictures in infants and children: 17 years’ experience and a literature review. J Pediatr Surg. 2003 Dec; 38(12): 1712-5.
  32. Lakhdar-Idrissi M., Khabbache K., Hida M. Esophageal endoscopic dilations. J Pediatr Gastroenterol Nutr. 2012 Jun; 54(6): 744-7.
  33. Shehata S.M., Enaba M.E. Endoscopic dilatation for benign oesophageal strictures in infants and toddlers: experience of an expectant protocol from North African tertiary centre. Afr J Paediatr Surg. 2012 Sep-Dec; 9(3): 187-92.
  34. Van der Zee D., Hulsker C. Indwelling esophageal balloon catheter for benign esophageal stenosis in infants and children. Surg Endosc. 2014 Apr; 28(4): 1126-30.
  35. Khanna S., Khanna S. Management of benign oesophageal strictures in children. Indian J Otolaryngol Head Neck Surg. 2008 Sep; 60(3): 218-22.
  36. Hsieh K.H., Soong W.J., Jeng M.J., Lee Y.S., Tsao P.C., Chou Y.L. Flexible endoscopic diagnosis and treatment of esophageal stenosis in children with noninvasive ventilation support. Pediatr Neonatol. 2018 Feb; 59(1): 31-4.
  37. Saito T., Ise K., Kawahara Y., Yamashita M., Shimizu H., Suzuki H., Gotoh M. Congenital esophageal stenosis because of tracheobronchial remnant and treated by circular myectomy: a case report. J Pediatr Surg. 2008 Mar; 43(3): 583-5.
  38. Serhal L., Gottrand F., Sfeir R., Guimber D., Devos P., Bonnevalle M., Storme L., Turck D., Michaud L. Anastomotic stricture after surgical repair of esophageal atresia: frequency, risk factors, and efficacy of esophageal bougie dilatations. J Pediatr Surg. 2010 Jul; 45(7): 1459-62.
  39. Türkyilmaz Z., Sönmez K., Demirtola A., Karabulut R., Poyraz A., Gülen S., Dinçer S., Başaklar A.C., Kale N. Mitomycin C prevents strictures in caustic esophageal burns in rats. J Surg Res. 2005 Feb; 123(2): 182-7.
  40. Gillespie M.B., Day T.A., Sharma A.K., Brodsky M.B., MartinHarris B. Role of mitomycin in upper digestive tract stricture. Head Neck. 2007 Jan; 29(1): 12-7.
  41. Jang C.H., Song C.H., Pak S.C. Effect of exposure to mitomycin C on cultured tympanic membrane fibroblasts. Int J Pediatr Otorhinolaryngol. 2003 Feb; 67(2): 173-6.
  42. Mearza A.A., Aslanides I.M. Uses and complications of mitomycin C in ophthalmology. Expert Opin Drug Saf. 2007 Jan; 6(1): 27-32.
  43. Günel E., Cağlayan F., Cağlayan O., Canbilen A., Tosun M. Effect of antioxidant therapy on collagen synthesis in corrosive esophageal burns. Pediatr Surg Int. 2002 Jan; 18(1): 24-7.
  44. Uhlen S., Fayoux P., Vachin F., Guimber D., Gottrand F., Turck D., Michaud L. Mitomycin C: an alternative conservative treatment for refractory esophageal stricture in children? Endoscopy. 2006 Apr; 38(4): 404-7.
  45. Berger M., Ure B., Lacher M. Mitomycin C in the therapy of recurrent esophageal strictures: hype or hope? Eur J Pediatr Surg. 2012 Apr; 22(2): 109-16.
  46. Rustagi T., Aslanian H.R., Laine L. Treatment of Refractory Gastrointestinal Strictures With Mitomycin C: A Systematic Review. J Clin Gastroenterol. 2015 Nov-Dec; 49(10): 837-47.
  47. Ley D., Bridenne M., Gottrand F., Lemale J., Hauser B., Lachaux A., Rebouissoux L., Viala J., Fayoux P., Michaud L. Efficacy and Safety of the Local Application of Mitomycin C to Recurrent Esophageal Strictures in Children. J Pediatr Gastroenterol Nutr. 2019 Nov; 69(5): 528-32.
  48. El-Asmar K.M., Hassan M.A., Abdelkader H.M., Hamza A.F. Topical mitomycin C application is effective in management of localized caustic esophageal stricture: a double-blinded, randomized, placebocontrolled trial. J Pediatr Surg. 2013 Jul; 48(7): 1621-7.
  49. Sweed A.S., Fawaz S.A., Ezzat W.F., Sabri S.M. A prospective controlled study to assess the use of mitomycin C in improving the results of esophageal dilatation in post corrosive esophageal stricture in children. Int J Pediatr Otorhinolaryngol. 2015 Jan; 79(1): 23-5.
  50. Spaander M.C., Baron T.H., Siersema P.D., Fuccio L., Schumacher B., Escorsell À., Garcia-Pagán J.C., Dumonceau J.M., Conio M., de Ceglie A., Skowronek J., Nordsmark M., Seufferlein T., Van Gossum A., Hassan C., Repici A., Bruno M.J. Esophageal stenting for benign and malignant disease: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline. Endoscopy. 2016 Oct; 48(10): 939-48.
  51. Tringali A., Thomson M., Dumonceau J.M., et al. Pediatric gastrointestinal endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) and European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) Guideline Executive summary. Endoscopy. 2017; 49(1): 83-91
  52. Rosseneu S., Afzal N., Yerushalmi B., Ibarguen-Secchia E., Lewindon P., Cameron D., Mahler T., Schwagten K., Köhler H., Lindley K.J., Thomson M. Topical application of mitomycin-C in oesophageal strictures. J Pediatr Gastroenterol Nutr. 2007 Mar; 44(3): 336-41.
  53. Kujawski K., Stasiak M., Rysz J. The evaluation of esophageal stenting complications in palliative treatment of dysphagia related to esophageal cancer. Med Sci Monit. 2012 May; 18(5): CR323-9.
  54. Vandenplas Y., Hauser B., Devreker T., Urbain D., Reynaert H. A biodegradable esophageal stent in the treatment of a corrosive esophageal stenosis in a child. J Pediatr Gastroenterol Nutr. 2009 Aug; 49(2): 254-7.
  55. Kochhar R., Poornachandra K.S. Intralesional steroid injection therapy in the management of resistant gastrointestinal strictures. World J Gastrointest Endosc. 2010 Feb 16; 2(2): 61-8.
  56. Alshammari J., Quesnel S., Pierrot S., Couloigner V. Endoscopic balloon dilatation of esophageal strictures in children. Int J Pediatr Otorhinolaryngol. 2011 Nov; 75(11): 1376-9.
  57. Jawad A.J., Al-Samarrai A.I., Al-Rabeeah A., Al-Rashed R. The management of esophageal strictures in children. Ann Saudi Med. 1995 Jan; 15(1): 43-7.
  58. Agrawal N, Morrison GA. Laryngeal cancer after topical mitomycin C application. J Laryngol Otol. 2006 Dec;120(12):1075-6.
  59. Jawad A.J., Al-Samarrai A.I., Al-Rabeeah A., Al-Rashed R. The management of esophageal strictures in children. Ann Saudi Med. 1995 Jan; 15(1): 43-7.
  60. Jayasekera C.S., Desmond P.V., Holmes J.A., Kitson M., Taylor A.C. Cluster of 4 cases of esophageal squamous cell cancer developing in adults with surgically corrected esophageal atresia--time for screening to start. J Pediatr Surg. 2012 Apr; 47(4): 646-51.
  61. Brzački V., Mladenović B., Jeremić L., Živanović D., Govedarović N., Dimić D., Golubović M., Stoičkov V. Congenital esophageal stenosis: a rare malformation of the foregut. Nagoya J Med Sci. 2019 Nov; 81(4): 535-47.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c)

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies