RESULTS OF SURGICAL TREATMENT OF NEWBORNS WITH ANTERIOR ABDOMINAL WALL MALFORMATIONS



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Introduction. Malformations of the anterior abdominal wall in newborns is one of the actual problems in neonatal surgery. Antenatal diagnostics of such defects as omphalocele and gastroschisis allows to diagnose and perform necessary surgical interventions in time. Often, outcomes of treatment of newborns with embryonic hernia depend not only on the form of the defect, but also on the accompanying abnomalies. Purpose. To present outcomes of surgical treatment of newborns with anterior abdominal wall malformations. Material and methods. From December 2017 till May 2019, 34 pregnant women with fetal anterior abdominal wall malformations were consulted; 17 out of them with omphalocele and gastroschisis were treated. Results. In December 2017, the surgical department for newborns and infants at the National Medical Research Center for Children’s Health successfully helped children with malformations of the anterior abdominal wall. 16 children were discharged home in a satisfactory condition; there was one unsatisfactory outcome. 11 patients were treated for gastroschisis; 6 patients were treated for omphalocele. 3 patients had repeated surgeries for concomitant pathologies. There were no any adhesive processes and commissural intestinal obstruction. Conclusions. In Russia, there are two groups of newborns with anterior abdominal wall defects: children with isolated defects and children with concomitant pathologies who have an increased risk of unsatisfactory outcomes. The technique developed by us for treating newborns with anterior abdominal wall malformations and concomitant pathologies has very good cosmetic and functional results and reduces the number of postoperative complications and unsatisfactory outcomes.

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A. Shchukina

National Medical Research Center for Children’s Health

编辑信件的主要联系方式.
Email: noemail@neicon.ru
ORCID iD: 0000-0001-6892-6860
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O. Mokrushina

National Medical Research Center for Children’s Health; Pirogov Russian National Research Medical University

Email: noemail@neicon.ru
ORCID iD: 0000-0002-8169-7342
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A. Gurskaya

National Medical Research Center for Children’s Health

Email: noemail@neicon.ru
ORCID iD: 0000-0002-0462-596X
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E. Dyakonova

National Medical Research Center for Children’s Health

Email: noemail@neicon.ru
ORCID iD: 0000-0002-8563-6002
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O. Nakovkin

National Medical Research Center for Children’s Health

Email: noemail@neicon.ru
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M. Sulavko

National Medical Research Center for Children’s Health

Email: noemail@neicon.ru
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D. Akhmedova

National Medical Research Center for Children’s Health

Email: noemail@neicon.ru
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参考

  1. Рузматов И.Б., Эргашев Б.Б. Диагностика и хирургическое лечение омфалоцеле у новорожденных. Детская хирургия. 2017; 21(3): 131-3.
  2. Кацупеев В.Б., Чепурной Г.И., Чепурной М.Г., Матвеев О.Л., Дадаян А.Г., Воловик К.Г., Бабич И.И., Хоронько Ю.В., Лукаш Ю.В. Редкое наблюдение сочетания омфалоцеле с изолированными энтерокистомами у новорожденного. Детская хирургия. 2019; 23(4): 215-7.
  3. Conner P., Vejde J.H., Burgos C.M. Accuracy and impact of prenatal diagnosis in infants with omphalocele. Pediatr Surg Int. 2018; 34(6): 629-33.
  4. Wright N.J., Sekabira J., Ade-Ajayi N. Care of infants with gastroschisis in low-resource settings. Semin Pediatr Surg. 2018; 27(5): 321-26.
  5. Sparks T.N., Shaffer B.L., Page J., Caughey A.B. Gastroschisis: mortality risks with each additional week of expectant management. Am J Obstet Gynecol. 2017; 216(1):66.e1-66.e7.
  6. Roux N., Jakubowicz D., Salomon L., Grangé G., Giuseppi A., Rousseau V., Khen-Dunlop N., Beaudoin S. Early surgical management for giant omphalocele: Results and prognostic factors. J. Pediatr. Surg. 2018; 53(10): 1908-13.
  7. Gamba P, Midrio P. Abdominal wall defects: prenatal diagnosis, newborn management, and long-term outcomes. Semin Pediatr Surg. 2014; 23(5): 283-90.
  8. Skarsgard E.D. Management of gastroschisis. Curr Opin Pediatr. 2016; 28(3): 363-69.
  9. Corey K.M., Hornik C.P., Laughon M.M., McHutchison K., Clark R.H., Smith P.B. Frequency of anomalies and hospital outcomes in infants with gastroschisis and omphalocele. Early Hum Dev. 2014; 90(8): 421-24.
  10. Horslev T., Binongo J.N., Kancherla V. Maternal. Chlamydia infection during pregnancy among younger mothers and risk of gastroschisis in singleton offspring. Birth Defects Res. 2018; 110(5): 429-42.
  11. Yazdy M.M., Mitchell A.A., Werler M.M. Maternal genitourinary infections and the risk of gastroschisis. Am J Epidemiol. 2014; 180(5): 518-25.
  12. Bhatt P., Lekshminarayanan A., Donda K., Dapaah-Siakwan F., Thakkar B., Parat S., Chabra S., Billimoria Z. Trends in incidence and outcomes of gastroschisis in the United States: analysis of the national inpatient sample 2010-2014. Pediatr Surg Int. 2018; 34(9): 919-29.
  13. Harris J., Poirier J., Selip D., Pillai S.N., Shah A., Jackson C.C., Chiu B. Early Closure of Gastroschisis After Silo Placement Correlates with Earlier Enteral Feeding. J Neonatal Surg. 2015; 4(3):28.
  14. Akram H. Aljahdali, Hussah M. Al-Buainain, Erik D. Skarsgard Staged closure of a giant omphalocele with amnion preservation, modified technique. Saudi Med J. 2017; 38(4): 422-4.
  15. Ekerete A. Ekot, Victor C. Emordi, David O. Osifo. Does omphalocele major undergo spontaneous closure? J Surg Case Rep. 2017; 8: 1-3.
  16. Lubinsky M. A vascular and thrombotic model of gastroschisis. Am J Med Genet A. 2014; 164A(4): 915-17.
  17. Watanabe S., Suzuki T., Hara F., Yasui T., Uga N., Naoe A. Omphalocele and Gastroschisis in Newborns: Over 16 Years of Experience from a Single Clinic. J Neonatal Surg. 2017; 6(2): 27.
  18. Zahouani T., Mendez M.D. Omphalocele. Eur J Med Genet. 2018 Sep; 61(9): 499-507.
  19. Wright N.J., Zani A., Ade-Ajayi N. Epidemiology, management and outcome of gastroschisis in Sub-Saharan Africa: Results of an international survey. Afr J Paediatr Surg. 2015; 12(1): 1-6.
  20. Jones A.M., Isenburg J., Salemi J.L., Arnold K.E., Mai C.T., Aggarwal D., Arias W., etc. Increasing Prevalence of Gastroschisis-14 States, 1995-2012 MMWR. Morb Mortal Wkly Rep. 2016; 65(2): 23-6.
  21. Allman R., Sousa J., Walker M.W., Laughon M.M., Spitzer A.R., Clark R.H.The epidemiology, prevalence and hospital outcomes of infants with gastroschisis. J Perinatol. 2016; 36(10): 901-05.
  22. Lammer E.J., Iovannisci D.M., Tom L., Schultz K., Shaw G.M. Gastroschisis: a gene-environment model involving the VEGF-NOS3 pathway. Am J Med Genet C Semin Med Genet. 2008; 148C(3): 213-18.
  23. Mills J.L., Druschel C.M., Pangilinan F., Pass K., Cox C., Seltzer R.R., Conley M.R., Brody L.C. Folate-related genes and omphalocele. Am J Med Genet A. 2005; 136(1): 8-11.
  24. Mills J.L., Carter T.C., Kay D.M., Browne M.L., Brody L.C., Liu A., Romitti P.A., Caggana M., Druschel C.M. Folate and vitamin B12-related genes and risk for omphalocele. Hum Genet. 2012; 131(5): 739-46.
  25. Meyer M.R., Shaffer B.L., Doss A.E., Cahill A.G., Snowden J.M., Caughey A.B. Prospective risk of fetal death with gastroschisis. J Matern Fetal Neonatal Med. 2015; 28(17): 2126-9.
  26. Salinas-Torres V.M., Salinas-Torres R.A., Cerda-Flores R.M., Gallardo-Blanco H.L., Martínez-de-Villarreal L.E. A clinical-pathogenetic approach on associated anomalies and chromosomal defects supports novel candidate critical regions and genes for gastroschisis. Pediatr Surg Int. 2018; 34(9): 931-43.
  27. Kristin M. Corey, Christoph P. Hornik, Matthew M. Laughon, Kerstin McHutchison, Reese H. Clark, and P. Brian Smith. Frequency of Anomalies and Hospital Outcomes in Infants with Gastroschisis and Omphalocele. Early Hum Dev. 2014; 90(8): 421-4.
  28. Padula A.M., Yang W., Schultz K., Tom L., Lin B., Carmichael S.L., Lammer E.J., Shaw G.M. Gene variants as risk factors for gastroschisis. Am J Med Genet A. 2016; 170(11): 2788-802.
  29. Nazer Herrera J., Karachon Essedin L., Cifuentes Ovalle L., Assar Cuevas R. Gastroschisis: A pandemic with increasing rates? ECLAMC experience in Chile 1982-2015. Rev Chil Pediatr. 2016; 87(5): 380-86.
  30. Hale J., Derbyshire A., Taylor A., Osmond C., Wellesley D., Howe D.T. Relationship between neonatal gastroschisis and maternal body mass index in a United Kingdom population. Eur J Obstet Gynecol Reprod Biol. 2017; 210: 292-94.
  31. Centofanti S.F., Francisco R.P.V., Phillippi S.T., Castro I.A., Hoshida M.S., Curi R., Brizot M.L. Low serum fatty acid levels in pregnancies with fetal gastroschisis: A prospective study. Am J Med Genet A. 2018.; 176(4): 915-24.
  32. Fleurke-Rozema H., van de Kamp K., Bakker M., Pajkrt E., Bilardo C., Snijders R. Prevalence, timing of diagnosis and pregnancy outcome of abdominal wall defects after the introduction of a national prenatal screening program. Prenat Diagn. 2017; 37(4): 383-88.

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