APPENDICULAR PERITONITIS IN CHILDREN: AN EFFICIENT SURGICAL APPROACH AND INTENSIVE CARE



如何引用文章

全文:

详细

Introduction. Currently, there is no any unified approach to the treatment of complicated forms of acute appendicitis in children. The purpose of our study is to evaluate the effectiveness of the local Protocol for diagnostics and treatment of appendicular peritonitis (AP) in children. Material and methods. 149 children with AP, aged 2 - 17 (11 ± 3.5 ), were included into the study. All of them were treated at the Clinical and Research Institute Emergency Pediatric Surgery and Trauma (CRIEPST) in 2015-2018. In the gender structure, boys (104; 69.8%) prevailed over girls (45; 30.2%). The following parameters were evaluated: AP structure, surgical tactics, postoperative course (incidence of postoperative intestinal failure syndrome (IFS), postoperative complications, length of hospital stay). A tactics for surgical treatment and volume of intensive care in the postoperative period were defined depending on AP severity and according to the local Protocol. Laparoscopic appendectomy was performed in 145 (97.3%) patients. There were no intraoperative complications and conversions in the studied group. In case of periappendiular abscess (PA) 3 (2.7%), patients had puncture and abscess drainage under ultrasound control. Results. While analyzing the AP structure by forms , the following picture was shown: free and abscessed forms were approximately equal - 72 (48.3%) and 77 (51.7%), respectively (p > 0.05). Diffuse peritonitis - 31.5%; generalized - 16.8%; combined - 17.4%; periappendicular abscess (PA) stage 1-14.8%; PA 2-16.8%; PA 3-2.7%. Postoperative complications - 4 (2.7%): postoperative abdominal abscesses - 3 (2.0%); early adhesive intestinal obstruction - 1 (0.7%). In postoperative abscesses, puncture and drainage were performed under ultrasound control; in early adhesive intestinal obstruction - laparoscopic adhesiolysis. All the children recovered. Length of intensive care was 2.9 ± 1.8 days; hospitalization - 12.0 ± 5.2 days. Conclusion. The local Protocol developed by the researchers helps to define a surgical tactics and volume of intensive care in the postoperative period. Laparoscopic surgery, in the vast majority of cases, is an optimal and effective technique for AP surgical treatment in children. Contraindications to laparoscopic surgery are PA 3 and total abscessing peritonitis.

作者简介

O. Karaseva

Clinical and Research Institute of Emergency Pediatric Surgery and Trauma

编辑信件的主要联系方式.
Email: noemail@neicon.ru
ORCID iD: 0000-0001-9418-4418
俄罗斯联邦

K. Utkina

Clinical and Research Institute of Emergency Pediatric Surgery and Trauma

Email: dr_utkina@mail.ru
ORCID iD: 0000-0003-3639-9394
俄罗斯联邦

A. Gorelik

Clinical and Research Institute of Emergency Pediatric Surgery and Trauma

Email: noemail@neicon.ru
ORCID iD: 0000-0003-1746-8446
俄罗斯联邦

A. Timofeeva

Clinical and Research Institute of Emergency Pediatric Surgery and Trauma

Email: noemail@neicon.ru
ORCID iD: 0000-0002-6940-4535
俄罗斯联邦

D. Golikov

Clinical and Research Institute of Emergency Pediatric Surgery and Trauma

Email: noemail@neicon.ru
ORCID iD: 0000-0001-5982-5494
俄罗斯联邦

T. Ivanova

Clinical and Research Institute of Emergency Pediatric Surgery and Trauma

Email: noemail@neicon.ru
俄罗斯联邦

L. Roshal

Clinical and Research Institute of Emergency Pediatric Surgery and Trauma; National Medical Research Center for Children’s Health

Email: noemail@neicon.ru
ORCID iD: 0000-0002-6920-7726
俄罗斯联邦

参考

  1. Addiss D.G., Shaffer N., Fowler B.S., Tauxe R.V. The epidemiology of appendicitis and appendectomy in the United States. Am J Epidemiol. 1990 Nov; 132(5): 910-25.
  2. Aarabi S., Sidhwa F., Riehle K.J., Chen Q., Mooney D.P. Pediatric appendicitis in New England: epidemiology and outcomes. J Pediatr Surg. 2011;46(6): 1106-14.
  3. Карасева О.В., Рошаль Л.М., Брянцев А.В., Капустин В.А., Чернышева Т.А., Иванова Т.Ф. Лечение аппендикулярного перитонита у детей. Детская хирургия. 2007; 3: 23-7.
  4. Дронов А.Ф., Котлобовский В.И., Поддубный И.В. Лапароскопическая аппендэктомия. Эндоскопическая хирургия. 2000; 1: 16-10.
  5. Коровин С.А., Соколов Ю.Ю. Лапароскопия при лечении детей острым аппендицитом и перитонитом. РМЖ. 2011; 22: 1396.
  6. Almaramhy H.H. Acute appendicitis in young children less than 5 years: review article. Ital J Pediatr. 2017; 43:15. Published online 2017 Jan 26. doi: 10.1186/s13052-017-0335-2
  7. Livingston E.H., Woodward W.A., Sarosi G.A., Haley R.W. Disconnect between incidence of nonperforated and perforated appendicitis: implications for pathophysiology and management. Ann Surg. 2007; 245: 886-892. doi: 10.1097/01.sla.0000256391.05233.aa
  8. Randen A., Laméris W., Es H.W., Heesewijk H.P., Ramshorst B., Ten Hove W., Bouma W.H., Leeuwen M.S., Keulen E.M., Bossuyt P.M., Stoker J., Boermeester M.A.; OPTIMA Study Group: A comparison of the accuracy of ultrasound and computed tomography in common diagnoses causing acute abdominal pain. Eur Radiol. 2011; 21: 1535-1545
  9. Schuler J.G., Shortsleeve M.J., Goldenson R.S., Perez-Rossello J.M., Perlmutter R.A., Thorsen A. Is there a role for abdominal computed tomographic scans in appendicitis? Arch Surg. 1998; 133: 373-377.
  10. Moberg A.C., Ahlberg G., Leijonmarck C., Montgomery A., Reiertsen O., Rosseland A.R., Stoerksson R. Diagnostic laparoscopy in 1,043 patients with suspected acute appendicitis. Eur J Surg. 1998; 164: 833-840.
  11. Elisabeth M.L. de Wijkerslooth, Anne Loes van den Boom, Bas P.L. WijnhovenVariation in Classification and Postoperative Management of Complex Appendicitis: A European Survey. World J Surg. 2019; 43(2): 439-446. Published online. 2018; Sep 25. doi: 10.1007/s00268-018-4806-4
  12. Biondi A., Di Stefano C., Ferrara F., Bellia A., Vacante M., Piazza L. Laparoscopic versus open appendectomy: a retrospective cohort study assessing outcomes and cost-effectiveness. World J Emerg Surg. 2016 Aug 30; 11(1): 44. doi: 10.1186/s13017-016-0102-5, 2016.
  13. Dai L., Shuai J. Laparoscopic versus open appendectomy in adults and children: A meta-analysis of randomized controlled trials. United European Gastroenterol J. 2016; 5(4): 542-553. doi: 10.1177/2050640616661931
  14. Wang X., Zhang W., Yang X., Shao J., Zhou X., Yuan J. Complicated appendicitis in children: is laparoscopic appendectomy appropriate? A comparative study with the open appendectomy-our experience. J Pediatr Surg. 2009 Oct; 44(10): 1924-7.
  15. Guanà R., Lonati L., Garofalo S. et al. Laparoscopic versus Open Surgery in Complicated Appendicitis in Children Less Than 5 Years Old: A Six-Year Single-Centre Experience. Surg Res Pract. 2016; 2016: 4120214. doi: 10.1155/2016/4120214
  16. Domene C.E., Volpe P., Heitor F.A. Three port laparoscopic appendectomy technique with low cost and aesthetic advantage. Arq Bras Cir Dig. 2014; 27 Suppl 1: 73-76. doi: 10.1590/S0102-6720201400S100018
  17. Said M., Ledochowski M., Dietze O., Simader H. Colonoscopic diagnosis and treatment of acute appendicitis. Eur J GastroenterolHepatol. 1995; 7(6): 569-571.
  18. Liu B.R., Song J.T., Han F.Y., Li H. et al. Endoscopic retrograde appendicitis therapy: a pilot minimally invasive technique (with videos). Gastrointest Endosc. 2012; 76: 243-247.9.
  19. Liu B.R., Ma X., Feng J., et al. Endoscopic retrograde appendicitis therapy (ERAT): a multicenter retrospective study in China. Surg Endosc. 2015; 29: 905-909
  20. BouHaidar D.S., Bawany M.Z., Schubert M.L. ERAT: A New ERA for Appendicitis Therapy? Dig Dis Sci, 61(11): 3099-3101, 01 Nov 2016
  21. Bulian D.R., Kaehler G., Magdeburg R., Butters M., Burghardt J., Albrecht R. et al. Analysis of the First 217 Appendectomies of the German NOTES Registry. Ann Surg. 2017 Mar; 265(3): 534-538. doi: 10.1097/SLA.0000000000001742.
  22. Hybrid transgastric appendectomy is feasible but does not offer advantages compared with laparoscopic appendectomy: Results from the transgastric appendectomy study. Surgery. 2017 Aug;162(2): 295-302. doi: 10.1016/j.surg.2017.02.013. Epub 2017 Apr
  23. Simillis C., Symeonides P., Shorthouse A.J., Tekkis P.P. A meta-analysis comparing conservative treatment versus acute appendectomy for complicated appendicitis (abscess or phlegmon). Surgery. 2010; 147: 818-829.
  24. Talan D.A., Moran G.J., Saltzman D.J. Nonoperative management of appendicitis: avoiding hospitalization and surgery. J Am Coll Surg. 2017; 224: 994.
  25. Steiner Z., Buklan G., Gutermacher M., Litmanovitz I., Landa T., Arnon S. Conservative antibiotic treatment for acute uncomplicated appendicitis is feasible. Pediatr Surg Int. 2018; 34: 283-288.
  26. Shindoh J., Niwa H., Kawai K., Ohata K., Ishihara Y., Takabayashi N. et al. Predictive factors for negative outcomes in initial non-operative management of suspected appendicitis. J Gastrointest Surg. 2010 Feb; 14: 309-314.
  27. Loftus T.J., Brakenridge S.C., Croft C.A., Stephen Smith R., Efron P.A., Moore F.A. et al. Successful nonoperative management of uncomplicated appendicitis: predictors and outcomes. J Surg Res. 2018; 222: 212-218.
  28. Карасева О.В. Абсцедирующие формы аппендикулярного перитонита у детей. Докт. дисс, Москва, 2006

补充文件

附件文件
动作
1. JATS XML

版权所有 © , 2020

##common.cookie##