A comparative analysis of outcomes after surgical reconstruction of stenoses in the upper respiratory tract in children



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Introduction. Definition " upper respiratory tract stenosis " (URTS) includes a large number of nosologies. The most common are cicatricial stenoses, in particular, post-intubation ones as well as bilateral paralysis of the larynx. An important issue for nowadays is choosing the curative modality for such patients.

Purpose. To compare outcomes after treating children with URTS.

Material and methods. The authors have assessed results of treatment of 110 patients who had reconstructive surgery in 2010-2019. Patients were divided into two groups depending on the nosology: stenosis of the upper respiratory tract (n = 71) and bilateral paralysis of the larynx (n-39). In each group, four types of surgeries were performed: costal cartilage plasty, plasty with T-tube (TT), a modified version of plasty with TT, plasty with a stent. The choice of treatment technique was determined mostly by the tendency to make this or that type of surgery in authors' departments, as well as by the nosology, severity of the disease and patient's age. Decannulation terms, surgical time, early and late postoperative complications as well as relapse-free period were assessed.

Results. 66% patients were decannulated in Group 1; in Group 2 - 69%. Group 1 a statistically reliable comparison was possible between the following techniques: costal cartilage plasty and laryngeal stent plasty (p > 0.005) as well as plasty with TT implantation and the proposed modified technique (p > 0.005). While using Mann-Whitney test and Log Rank, the authors found out that in Group 1 there were no significant difference in surgical time, relapse-free period and stenosis degree (p > 0.005). However, decannulation terms after plastic surgery of the larynx with costal cartilage implantation are longer than after plastic surgery with stent implantation (p < 0.005). In Group 2, the authors compared three abovementioned curative modalities, excluding laryngeal plasty with TT implantation. Thus, surgical time for costal cartilage plasty is longer, if to compare to other two techniques (p < 0.005). There is also no significant difference in decannulation terms and relapse-free periods between all three techniques (p > 0.005).

Conclusion. The results obtained have demonstrated the effectiveness of long-term stenting with TT placement in children, mainly with cicatricial stenoses, and in older children. The trial also revealed that laryngoplasty with costal cartilage in children with bilateral laryngeal paralysis is an effectiveness choice too.

作者简介

A. Razumovsky

Pirogov Russian National Research Medical University

Email: fake@neicon.ru
ORCID iD: 0000-0002-9497-4070

Moscow, 117997

俄罗斯联邦

Z. Mitupov

Pirogov Russian National Research Medical University

Email: fake@neicon.ru
ORCID iD: 0000-0002-0016-6444

Moscow, 117997

俄罗斯联邦

V. Rachkov

Pirogov Russian National Research Medical University

Email: fake@neicon.ru
ORCID iD: 0000-0002-1304-0592

Moscow, 117997

俄罗斯联邦

N. Stepanenko

Pirogov Russian National Research Medical University

Email: fake@neicon.ru
ORCID iD: 0000-0002-2827-1764

Moscow, 117997

俄罗斯联邦

A. Adler

Filatov City Children’s Hospital

Email: fake@neicon.ru
ORCID iD: 0000-0001-6084-8263

Moscow, 103001

俄罗斯联邦

N. Kulikova

Filatov City Children’s Hospital

Email: fake@neicon.ru
ORCID iD: 0000-0003-0834-2630

Moscow, 103001

俄罗斯联邦

D. Strizhova

Pirogov Russian National Research Medical University

编辑信件的主要联系方式.
Email: strizhova_d@mail.ru

Darya N. Strizhova, MD, post-graduate student at chair of pediatric surgery

Moscow, 117997

俄罗斯联邦

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