To the question of analgesia support of children in traumatologists’ outpatient practice

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BACKGROUND: The problem of adequate anesthesia in children with injuries at the prehospital stage do exists due to the lack of a universal approach to the assessment of pain syndrome intensity as well as to age restrictions for a number of medical preparations , and to difficulties in communication with young children.

AIM: To improve the quality of specialized outpatient emergency medical care for children with traumatic injuries.

METHODS: The present survey was conducted for one month, and 113 orthopedic traumatologists from children's trauma centers and emergency traumatologic and orthopedics departments of medical organizations subordinated to the Moscow Healthcare Department participated in it. Each participant was offered a questionnaire having 24 thematic sections on analgesics application in their outpatient practice at various stages of prehospital care for children with mild and moderate traumatic injuries. At the same time, in a number of sections, several answers could be selected by a participant.

RESULTS: The obtained results demonstrated that there is no any unified systematic approach to the pain management after mild and moderate injuries in children. Analgesia techniques at the outpatient stage are paid not enough attention. Many doctors are ready to give a detailed consultation on how to relief pain at home, but in some cases, parents themselves decide on how to do it, though they do not have necessary knowledge.

CONCLUSION: To develop indications for anesthesia support requires the implementation of specialized pain assessment scales differentiated by age groups, development of methodological recommendations and standards for analgesics application at the prehospital stage with comprehensive information on existing forms and age-related features of effective and safe medical preparations of recent generations.

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作者简介

Dmitry Vybornov

The Russian National Research Medical University named after N.I. Pirogov; Filatov N.F. Children's City Hospital

Email: vybornovdy@zdrav.mos.ru
ORCID iD: 0000-0001-8785-7725
SPIN 代码: 2660-5048

MD, Dr. Sci. (Medicine), Professor

俄罗斯联邦, Moscow; 15 Sadovaya-Kudrinskaya street, 123001 Moscow

Aleksandr Nekrutov

Research Institute for Healthcare Organization and Medical Management; Clinical and Research Institute of Emergency Pediatric Surgery and Trauma

编辑信件的主要联系方式.
Email: nekrutovav@zdrav.mos.ru
SPIN 代码: 6600-8961

MD, Cand. Sci. (Medicine)

俄罗斯联邦, Moscow; Moscow

Nikolay Semenov

Research Institute for Healthcare Organization and Medical Management

Email: semenovnyu@mail.ru

MD

俄罗斯联邦, Moscow

Konstantin Khmelnitsky

Research Institute for Healthcare Organization and Medical Management

Email: semenovnyu@mail.ru

MD

俄罗斯联邦, Moscow

Andrey Ilyin

Research Institute for Healthcare Organization and Medical Management

Email: IlinAO@zdrav.mos.ru

MD

俄罗斯联邦, Moscow

参考

  1. Lebedeva RN, Nikoda VV. Pharmacotherapy of acute pain. Moscow: AirArt; 1998. 184 p. (In Russ.)
  2. Vane AV, Avrutsky MYa. Pain and pain relief. Moscow: Meditsina; 1997. 173 p. (In Russ.)
  3. MacPherson RD. New directions in pain management. Drugs Today. 2002;38(2):135–145. doi: 10.1358/dot.2002.38.2.668325
  4. WHO Guidelines Approved by the Guidelines Review Committee. WHO guidelines on the pharmacological treatment of persisting pain in children with medical illnesses. Geneva: World Health Organization; 2012.
  5. WHO Guidelines Approved by the Guidelines Review Committee. WHO guidelines for the pharmacological and radiotherapeutic management of cancer pain in adults and adolescents. Geneva: World Health Organization; 2018.
  6. Gausche-Hill M, Brown KM, Oliver ZJ, et al. An evidence-based guideline for prehospital analgesia in trauma. Prehosp Emerg Care. 2014;18(Suppl. 1):25–34. doi: 10.3109/10903127.2013.844873
  7. Hartshorn S, Durnin S, Lyttle MD, Barrett M. Pain management in children and young adults with minor injury in emergency departments in the UK and Ireland: A PERUKI service evaluation. BMJ Paediatr Open. 2022;6(1):e001273. doi: 10.1136/bmjpo-2021-001273
  8. Holak A, Czapla M, Zielinska M. Pre-hospital pain management in children with Injuries: A retrospective cohort study. J Сlin Med. 2021;10(14):3056. doi: 10.3390/jcm10143056
  9. Jaeger A, Dudley N, Holsti M, et al. Impact of an offline pain management protocol on prehospital provider self-efficacy: A randomized trial. Pediatr Emerg Care. 2017;33(6):388–395. doi: 10.1097/PEC.0000000000000657
  10. Míguez-Navarro MC, Escobar-Castellanos M, Guerrero-Márquez G, et al. Pain prevalence among children visiting pediatric emergency departments. Pediatr Emerg Care. 2022;38(5):228–234. doi: 10.1097/PEC.0000000000002580
  11. Murphy A, McCoy S, Kay O'Reilly K, et al. A prevalence and management study of acute pain in children attending emergency departments by ambulance. Prehosp Emerg Care. 2016;20(1):52–58. doi: 10.3109/10903127.2015.1037478
  12. Chumpitazi CE, Chang C, Atanelov Z, et al. Managing acute pain in children presenting to the emergency department without opioids. J Am Coll Emerg Physicians Open. 2022;3(2):e12664. doi: 10.1002/emp2.12664
  13. O’Donnell FT. Pediatric pain management: A review. Mo Med. 2014;111(3):231–237.
  14. Poonai N, Bhullar G, Lin K, et al. Oral administration of morphine versus ibuprofen to manage postfracture pain in children: A randomized trial. CMAJ. 2014;186(18):1358–1363. doi: 10.1503/cmaj.140907
  15. Poddighe D, Brambilla I, Licari A, Marseglia GL. Ibuprofen for pain control in children: New value for an old molecule. Pediatr Emer Care. 2019;35(6):448–453. doi: 10.1097/PEC.0000000000001505
  16. Krivoshapkin AL. The physiology of pain. Modern concepts and mechanisms. A review of foreign literature. In: Pain and its treatment. Pain Research Portal [Internet]. Novosibirsk: The Interregional Public Siberian Anti-Pain Fund, 2023 [cited 2024 Mar 15]. Available from: https://painstudy.ru/matls/review/fizio.htm
  17. Garcia-Larrea L, Magnin M. Pathophysiology of neuropathic pain: Review of experimental models and proposed mechanisms. Press Med. 2008;37(2, Pt. 2):315–340. doi: 10.1016/j.lpm.2007.07.025
  18. Nikoda VV, Mayachkin RB. The use of analgesic based on ibuprofen and codeine (Nurofen Plus) in the postoperative period. RMJ (Russ Med J). 2002;10(21):978–984. (In Russ.) EDN: YVNFWF
  19. Vetrov VP, Dlin VV. Rational use of antipyretics in children. A manual for doctors. Moscow; 2002. 207 p. (In Russ.)
  20. Calvani M. Sindrome di Reye: morte di una sindrome? (O morire per una sindrome?) (In Italian). Recenti Prog Med. 2000;91(12):675–680.
  21. Center for Disease Control. National Reye syndrome surveillance — United States. N Engl J Med. 1999;(340):1377.
  22. Hedenmalm K, Spigset O. Agranulocytosis and other blood dyscrasias associated with dipyrone (metamizole). Eur J Clin Pharmacol. 2002;58(4):265–274. doi: 10.1007/s00228-002-0465-2
  23. Ushkalova EA, Astahova AV. Analgin safety concerns. Farmateka. 2003;(1):74–79. (In Russ.)
  24. Bertin L, Pons G, D'Athis P, et al. Randomized, doubleblind, multicenler, controlled trial of ibuprofen versus acetaminophen (paracetamol) and placebo for treatment of symptoms of tonsillitis and pharyngitis in children. J Pediatr. 1991;119(5):811–814. doi: 10.1016/s0022-3476(05)80308-7
  25. Lesko SM, Mitchell AA. Renal function after short-term ibuprofen use in infants and children. Pediatrics. 1997;100(6):954–957. doi: 10.1542/peds.100.6.954
  26. Autret E, Reboul-Marty J, Henry-Launois B, et al. Evaluation of ibuprofen versus aspirin and paracetamol on efficacy and comfort in children with fever. Eur J Clin Pharmacol. 1997;51(5):367–371. doi: 10.1007/s002280050215
  27. Argentieri J, Morrone K, Pollack Y. Acetaminophen and ibuprofen overdosage. Pediatr Rev. 2012;33(4):188–189. doi: 10.1542/pir.33-4-188
  28. Shepherd M, Aickin R. Paracetamol versus ibuprofen: A randomized controlled trial of outpatient analgesia efficacy for paediatric acute limb fractures. Emerg Med Australas. 2009;21(6):484–490. doi: 10.1111/j.1742-6723.2009.01232.x
  29. McQuay HJ, Moore RA. An evidencebased resource for pain relief. Oxford; New York: Oxford University Press; 1998.
  30. Geppe NA, Zaytseva OV. Ideas about the mechanisms of fever in children and the principles of antipyretic therapy. RMJ (Russ Med J). 2003;11(1):31–37. (In Russ.)
  31. The State Register of Medicines [Internet]. Moscow: Ministry of Health of Russian Federation; 2000–2024 [cited 17.05.2021]. Available from: https://grls.rosminzdrav.ru/ (In Russ.)
  32. Tatochenko VK. A pediatrician for every day. Handbook of drug therapy. Moscow; 2019. 224 р. (In Russ.)
  33. Zaytseva OV. Treatment of acute pain in children (review of international studies and clinical recommendations). Pediatrics. Consilium Medicum. 2019;(3):61–68. doi: 10.26442/26586630.2019.3.190624
  34. Zaytseva OV. Analgesics antipyretics in pediatrics. Pediatric pharmacology. 2008;5(2):76–81. EDN: KBXBZJ
  35. Vainilovich EG, Gorchakova AG, Burykin PS. Principles of managing children with pain syndrome. Zdravoohranenie (Minsk). 2015;(6):28–38. EDN: UCLGZF
  36. Tepaev RF, Obedin AN. Pain syndrome in children: Diagnosis and treatment. Pediatric pharmacology. 2014;11(6):86–91. EDN: TGIXAD doi: 10.15690/pf.v11i6.1222
  37. Ushkalova EA, Illarionova TS, Romanova OL. Comparative efficacy and safety of paracetamol and ibuprofen in children and pregnant women. Medical technologies: Assessment and choice. 2011;(2):9–15. EDN: OJMZKT
  38. Alyautdin RN, Lepakhin VK, Romanov BK, Pereverzev AP. On the safety of acetaminophen. Safety and risk of pharmacotherapy. 2014;(2):5–9. EDN: UCEGRF

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1. JATS XML
2. Fig. 1. The need for analgesia for children at the outpatient stage.

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3. Fig. 2. The time of receiving anesthesia.

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4. Fig. 3. The time from the moment of injury to receiving anesthesia.

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5. Fig. 4. The frequency of pain intensity assessment.

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6. Fig. 5. The popularity of pain assessment methods in children: ВАШ — is a visually analog scale; NIPS — Neonatal Infant Pain Scale; FLACC — Face, Legs, Activity, Cry, Consolability; CHIPPS — Children’s And Infants Postoperative Pain Scale; OPS — Objective Pain Scale.

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7. Fig. 6. Frequency of use of pain assessment methods in children: ВАШ — is a visually analog scale; NIPS — Neonatal Infant Pain Scale; FLACC — Face, Legs, Activity, Cry, Consolability; CHIPPS — Children’s And Infants Postoperative Pain Scale; OPS — Objective Pain Scale.

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8. Fig. 7. The frequency of documenting pain symptoms.

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9. Fig. 8. Factors preventing the documentation of pain symptoms.

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10. Fig. 9. The need for analgesia at the stage of primary administration.

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11. Fig. 10. The grounds for prescribing analgesia.

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12. Fig. 11. Drugs and methods of anesthesia at the initial admission.

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13. Fig. 12. The use of oral analgesics at the initial intake.

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14. Fig. 13. The validity of the choice of oral analgesics.

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15. Fig. 14. Drugs for analgesia in children under 12 years of age.

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16. Fig. 15. Drugs for analgesia in children over 12 years of age.

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17. Fig. 16. The frequency of anesthesia before performing manipulations.

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18. Fig. 17. The frequency of pain relief methods before performing manipulations.

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19. Fig. 18. The frequency of pain assessment in dynamics.

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20. Fig. 19. The frequency of issuing recommendations for analgesia at home after medical care.

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21. Fig. 20. The frequency of parents' requests for pain relief at home.

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22. Fig. 21. Factors in the administration of oral analgesics during home treatment.

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23. Fig. 22. The frequency of prescribing a detailed treatment regimen at home.

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24. Fig. 23. The frequency of use of drugs with a detailed treatment regimen at home.

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25. Fig. 24. The value of the prescription of an analgesic.

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版权所有 © Vybornov D.Y., Nekrutov A.V., Semenov N.Y., Khmelnitsky K.Y., Ilyin A.O., 2024

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