ENDOSCOPIC CORRECTION OF THE VESICOURETERAL REFLUX AFTER URETERAL REIMPLANTATION IN CHILDREN


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Introduction. Vesicoureteral reflux (VUR) is seen in 2 - 60% of patients after ureteral reimplantation. The present study summarizes the experience of several centers where endoscopic correction of the postoperative reflux was done with bulking preparations. Material and methods. A retrospective study including 43 patients (24 boys and 19 girls) with reflux of grade III-IV after various transvesical and extravesical ureteral reimplantations for primary megaureter, reflux, or kidney transplantation was performed. Exclusion criteria were: neurogenic bladder, posterior urethral valve and ureterocele. Patients’ age varied from 9 months to 17 years (average 70.6 months). VUR was unilateral in 40 patients and bilateral in 3 patients: a total number of operated ureters was 46. The interval between ureter reimplantation and endoscopic surgery ranged from 3 months to 8 years (average 18.9 months). Different biodegradable and stable bulking preparations were used in the procedure. Results. VUR was successfully corrected in 19 ureters (41.3%) after a single injection. The repeated procedure was performed in 14 ureters in case of decreased reflux grade after the first injection. In 5 ureters (35.7%), the reflux resolved after the repeated procedure. With the two mentioned injections, the total effectiveness of endoscopic VUR correction was 52.2%. There were no any ureteral obstruction. The only statistically significant factor affecting the effectiveness of treatment was the reflux degree. The effectiveness level for reflux grade III was 68.2% and for reflux grade IV - 37.5%. Conclusion. Endoscopic correction prevents ureter reimplantation in half of patients with a high grade of postoperative vesicoureteral reflux.

作者简介

V. Dubrov

2nd City Children’s Clinical Hospital

编辑信件的主要联系方式.
Email: dubroff2000@mail.ru
ORCID iD: 0000-0002-3705-1288
俄罗斯联邦

S. Bondarenko

Clinical Emergency Hospital No 7

Email: noemail@neicon.ru
ORCID iD: 0000-0001-5130-4782
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I. Kagantzov

Republican Children’s Clinical Hospital; Pitirim Sorokin Syktyvkar State University

Email: noemail@neicon.ru
ORCID iD: 0000-0002-3957-1615
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V. Sizonov

Regional Children’s Clinical Hospital; Rostov State Medical University

Email: noemail@neicon.ru
ORCID iD: 0000-0001-9145-8671
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参考

  1. Ширяев Н.Д., Каганцов И.М., Рачков Е.Б. и др. Всегда ли необходим рентгенологический контроль после хирургической коррекции первичного пузырно-мочеточникового рефлюкса. Детская хирургия. 2005; 9(1): 21-3
  2. Elder J.S. Guidelines for consideration for surgical repair of vesicoureteral reflux. Curr Opin Urol. 2000; 10(6): 5 79-85
  3. Дубров В.И., Бондаренко С.Г., Каганцов И.М. Модифицированная односторонняя лапароскопическая экстравезикальная антирефлюксная операция. Российский вестник детской хирургии, анестезиологии и реаниматологии. 2018; 2; 26-34.
  4. Марков Н.В., Каганцов И. М., Турабов И.А., Саблин Д. Е., Дубров В.И., Логваль А.А. Результаты оперативного лечения пузырно-мочеточникового рефлюкса высоких степеней у детей. Экспериментальная и клиническая урология. 2017; 3: 110-3.
  5. Калачик О.В., Жук Г.В., Дубров В.И., Кобяк А.Г., Чеботарева Т.К., Тур Н.И. и др. С. В. Пузырно-мочеточниковый рефлюкс, как фактор риска инфекции мочевых путей у реципиентов трансплантата почки детского возраста. Военная медицина. 2016; 3: 56-60.
  6. Ranchin B., Chapuis F., Dawhara M., Canterino I., Hadj-Aïssa A., Saïd M.H. et al. Vesicoureteral reflux after kidney transplantation in children. Nephrol Dial Transplant. 2000: 15(11): 1852-8.
  7. Hjälmås K., Löhr G., Tamminen-Möbius T., Seppänen J., Olbing H., Wikström S. Surgical Results in the International Reflux Study in Children (Europe). J Urol. 1992; 148(5Pt2): 1657-61.
  8. Neuhaus T.J., Schwöbel M., Schlumpf R., Offner G., Leumann E., Willi U. Pyelonephritis and vesicoureteral reflux after renal transplantation in young children. J Urol. 1997; 157(4): 1400-3.
  9. Krishnan A., Swana H., Mathias R., Baskin L.S. Redo ureteroneocystostomy using an extravesical approach in pediatric renal transplant patients with reflux: A retrospective analysis and description of technique. J Urol. 2006; 176(4 Pt 1): 1582-7.
  10. Gerhart J.P., Leonard M.P. Reoperative ureteral reimplantation: Strategies for management. J Pediatr Surg. 1991; 26(1): 58-63.
  11. Sheth K.R., White J.T., Stanasel I., Janzen N., Mittal A., Koh C.J. et al. Comparing treatment modalities for transplant kidney vesicoureteral reflux in the pediatric population. J Pediatr Urol. 2018; 14(6): 554.e1-6.
  12. Bar-Yosef Y., Castellan M., Joshi D., Labbie A., Gosalbez R. Salvage Dextranomer-Hyaluronic Acid Copolymer for Persistent Reflux After Ureteral Reimplantation: Early Success Rates. J Urol. 2011; 185: 2531-5.
  13. Matouschek E. Treatment of vesicorenal reflux by transurethral teflon-injection (author’s transl). Urologe A. 1981; 20(5): 263-4
  14. Дубров В.И., Строцкий А.В., Шкутов А.О., Скобеюс И.А. Результаты эндоскопической коррекции пузырно-мочеточникового рефлюкса у детей. Медицинский журнал. 2019; 4: 58-63
  15. Kumar R., Puri P. Endoscopic Correction of Vesicoureteric Reflux in Failed Reimplanted Ureters. Eur Urol. 1998; 33(1): 98-100.
  16. Kitchens D., Minevich E., DeFoor W., Reddy P., Wacksman J., Sheldon C. et al. Endoscopic injection of dextranomer/hyaluronicacid copolymer to correct vesicoureteral reflux following failed ureteroneocystostomy. J Urol. 2006; 176(4 Pt 2): 1861-3.
  17. Carrillo Arroyoa I., Fuentes Carreterob S., Gómez Fraile A., Morante Valverdea R., Tordable Ojedaa C., Cabezalí Barbanchoa D. Technical challenges of endoscopic treatment for vesicoureteral reflux after Cohen reimplantation. Actas Urol Esp. 2019; 43 (7): 384-8.
  18. Akiki A., Boissier R., Delaporte V., Maurin C., Gaillet S., Karsenty G. et al. Endoscopic Treatment of Symptomatic Vesicoureteral Reflux after Renal Transplantation. J Urol. 2015; 193(1): 225-9.
  19. Pichler R., Buttazzoni A., Rehder P., Bartsch G., Steiner H., Oswald J. Endoscopic application of dextranomer/hyaluronic acid copolymer in the treatment of vesico-ureteric reflux after renal transplantation. BJU Int. 2011; 107(12): 1967-72.
  20. Yucel S., Akin Y., Celik O., Erdogru T., Baykara M. Endoscopic vesicoureteral reflux correction in transplanted kidneys: Does injection technique matter? J Endourol. 2010; 24(10): 1661-4.
  21. Williams M.A., Giel D.W., Colleen Hastings M. Endoscopic Deflux injection for pediatric transplant reflux: A feasible alternative to open ureteral reimplant. J Pediatr Urol. 2008; 4(5): 341-4.
  22. Vemulakonda V.M., Koyle M.A., Lendvay T.S., Risk M.C., Kirsch A.J., Cheng E.Y. et al. Endoscopic treatment of symptomatic refluxing renal transplant ureteroneocystostomies in children. Pediatr Transpl. 2010; 14(2): 212-5.
  23. Cambareri G., Carpenter C., Stock J., Lewis J., Marietti S. Endoscopic antireflux surgery leading to obstruction in pediatric renal transplant patients. Pediatr Transpl. 2016; 21(1): e12838.

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