Povidon-iodine applied for the treatment of chylothorax in children


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Introduction. The aim of this study is to demonstrate the experience of non-surgical treatment of congenital and acquired chylothorax in children using povidone-iodine.

Material and methods. The study presents results of treatment of 10 patients with chylothorax who had chemical pleurodesis with povidone-iodine. The study covered a time period from 2016 to 2020. The congenital character of the disease was registered in 2 patients, the acquired one - in 8 patients. The main indication for surgery was ineffective conservative therapy, including the withdrawal of feeding and the administration of preparation Octreotide. The procedure consisted of intrapleural injection of 4% povidone-iodine solution into the pleural cavity with the calculated dose of 1 ml/kg and solution exposure for 4 hours. Results. The interpleural administration of povidone-iodine was effective in all patients. Complications of chemical pleurodesis were observed in 2 patients and were associated with pulmonary edema on the injection side. Lymph outflow was stopped on average in 4 days. There was one adverse episode which developed because of the lung malformation incompatible with life. Conclusions. Intrapleural administration of povidone-iodine is an effective treatment of chylothorax in children.

作者简介

Yu. Kozlov

Irkutsk Regional Children’s Clinical Hospital;
Irkutsk State Medical Academy of Continuous Education;
Irkutsk State Medical University

编辑信件的主要联系方式.
Email: yuriherz@hotmail.com
ORCID iD: 0000-0003-2313-897X

Yury A. Kozlov, Chief Doctor of the Irkutsk Regional Children’s Clinical Hospital; professor at department of pediatric surgery at the Irkutsk State Medical University; professor at department of pediatric surgery at the Irkutsk State Medical Academy of Continuing Education

664009, Irkutsk,

664003, Irkutsk,

664049, Irkutsk

俄罗斯联邦

K. Kovalkov

Kemerovo Clinical Pediatric Hospital

Email: fake@neicon.ru
ORCID iD: 0000-0001-6126-4198

650056, Kemerovo

俄罗斯联邦

S. Poloyan

Center for Maternity and Childhood Protection

Email: fake@neicon.ru
ORCID iD: 0000-0001-7042-6646

660074, Krasnoyarsk

俄罗斯联邦

P. Baradieva

Irkutsk Regional Children’s Clinical Hospital

Email: fake@neicon.ru
ORCID iD: 0000-0002-5463-6763

664000, Irkutsk

俄罗斯联邦

D. Zvonkov

Irkutsk State Medical University

Email: fake@neicon.ru
ORCID iD: 0000-0002-7167-2520

664003, Irkutsk

俄罗斯联邦

C. Ochirov

Irkutsk Regional Children’s Clinical Hospital

Email: fake@neicon.ru
ORCID iD: 0000-0002-6045-1087

664000, Irkutsk

俄罗斯联邦

V. Cheremnov

Irkutsk Regional Children’s Clinical Hospital

Email: fake@neicon.ru
ORCID iD: 0000-0001-6135-4054

664000, Irkutsk

俄罗斯联邦

V. Kapuller

Assuta University Medical Center, Ben-Gurion University

Email: fake@neicon.ru
ORCID iD: 0000-0003-0076-5778

Ashdod

以色列

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