Endosurgery in the treatment of children with liver tumors
- Authors: Riabov A.b1,2, Poddubnyi I.V.2,3, Trunov V.O.2,4, Kurkin A.P.2, Kubirov M.S.2, Khizhnikov A.V.2, Milashchenko T.A.2, Medvedeva A.O.2, Rykov M.Y.5
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Affiliations:
- National Medical Research Radiological Centre
- Morozov Children Municipal Clinical Hospital
- Evdokimov Moscow State University of Medicine and Dentistry
- Pirogov Russian National Research Medical University
- Tver State Medical University
- Issue: Vol 25, No 5 (2021)
- Pages: 296-302
- Section: ORIGINAL STUDY
- Submitted: 16.11.2021
- Accepted: 16.11.2021
- Published: 16.11.2021
- URL: https://jps-nmp.ru/jour/article/view/371
- DOI: https://doi.org/10.55308/1560-9510-2021-25-5-296-302
- ID: 371
Cite item
Abstract
Introduction. The basic technique for treating patients with liver neoplasms is a surgical one. Currently, there is a trend to decrease a traumatic impact. One of the options for this is to develop and to implement minimally invasive surgical techniques which make postoperative period and rehabilitation easier.
Purpose. To find out the most optimal tactics for surgical treatment of children with liver tumors.
Material and methods. In 2014-2020, 26 patients, aged 0-17 years, with liver tumors were treated in Morozov Children’s City Clinical Hospital. 16 boys (61.5%) and 10 girls (38.5%). 17 patients with hepatoblastomas (68%); 2 (8%) in twos - hepatocellular cancer, embryonic liver sarcomas and focal nodular hyperplasias; 1 (4%) by ones - adenoma and hamartomas. In the morphological picture, hepatoplastoma was the most common (16 patients). 25 liver resections were performed; in 5 out of them (20%) (patients aged 3-9 years) minimally invasive technologies were used.
Results. Surgical time was significantly shorter in patients who were operated on with laparoscopic access (30–60 minutes), if to compare with laparotomic access (180-270 minutes). The volume of intraoperative blood loss in laparotomic access is more than 5 times larger than in laparoscopic access. In the group of patients operated on with the open access, intraoperative complications were noted in 2 (8%) cases: lethal outcome (4%) and injury of the extrahepatic biliary tract (4%).
Conclusion. Laparoscopic techniques reduce surgical time and blood loss. They also prevent complications both during surgery and in the postoperative period, shorten the hospital stay and promote early patient’s mobilization and early enteral feedings as well as early chemotherapy; they reduce pharmpreparation loading and prepare conditions for radical surgery
About the authors
A. b Riabov
National Medical Research Radiological Centre; Morozov Children Municipal Clinical Hospital
Author for correspondence.
Email: fake@neicon.ru
ORCID iD: 0000-0002-1037-2364
125284, Moscow, Russian Federation
119049, Moscow, Russian Federation
РоссияI. V. Poddubnyi
Morozov Children Municipal Clinical Hospital; Evdokimov Moscow State University of Medicine and Dentistry
Email: fake@neicon.ru
119049, Moscow, Russian Federation
127473, Moscow, Russian Federation
РоссияV. O. Trunov
Morozov Children Municipal Clinical Hospital; Pirogov Russian National Research Medical University
Email: fake@neicon.ru
119049, Moscow, Russian Federation
117997, Moscow, Russian Federation
РоссияA. P. Kurkin
Morozov Children Municipal Clinical Hospital
Email: fake@neicon.ru
ORCID iD: 0000-0001-6142-9511
119049, Moscow, Russian Federation
РоссияM. S. Kubirov
Morozov Children Municipal Clinical Hospital
Email: fake@neicon.ru
119049, Moscow, Russian Federation
РоссияA. V. Khizhnikov
Morozov Children Municipal Clinical Hospital
Email: fake@neicon.ru
ORCID iD: 0000-0001-7914-651X
119049, Moscow, Russian Federation
РоссияT. A. Milashchenko
Morozov Children Municipal Clinical Hospital
Email: fake@neicon.ru
119049, Moscow, Russian Federation
РоссияA. O. Medvedeva
Morozov Children Municipal Clinical Hospital
Email: fake@neicon.ru
119049, Moscow, Russian Federation
РоссияM. Yu. Rykov
Tver State Medical University
Email: wordex2006@rambler.ru
ORCID iD: 0000-0002-8398-7001
Maxim Yu. Rykov – MD, Dr.Sc. (med), associate professor, Vice-rector for research and innovation, professor of the department of oncology, surgery and palliative medicine
170100, Tver, Russian Federation
РоссияReferences
- Альперович Б.И. Хирургия печени. Томск: Издательство Томского университета. 1983; 352.
- Wendel W. Beitrage zur Chiryrgie der Leber. Arch. Clin. Chir. 1911; 95: 887.
- Кузнецов М.М., Пенский Ю.Р. О способах резекции печени. Хирургический вестник. 1894; 12(10–11): 711-31.
- Дыхно A.M. К вопросу об обширных резекциях печени. Вестник хирургии. 1955; 4: 117-9.
- Заривчацкий М.Ф., Мугатаров И.Н., Каменских Е.Д., Косяк А.А., Гаврилов О.В., Мальгинов К.Е., Колеватов А.П. Профилактика и лечение осложнений при резекциях очаговых образований печени. Анналы хирургической гепатологии. 2013; 18(3): 47-53.
- Shirabe K., Kajiyama K., Harimoto N., Tsujita E., Wakiyama S., Maehara Y. Risk factors for massive bleeding during major hepatectomy. Wld. J. Surg. 2010; 34(7): 1555-62.
- Reich H., McGlynn F., DeCaprio J., Budin R. Laparoscopic excision of benign liver lesions. Obstet Gynecol. 1991; 78(5): 956-8.
- Azagra J.S., Goergen M., Gilbart E., Jacobs D. Laparoscopic anatomical (hepatic) left lateral segmentectomy-technical aspects. Surg. Endosc. 1996; 10(7): 758-61.
- Fabiani P., Katkhouda N., Lovine L., et al. Laparoscopic fenestration of biliary cysts. Surg Endosc. 1991; 1(3): 162-5.
- Rau H.G., Meyer G, Cohnert T.U. et al. Laparoscopic liver resection with the water-jet dissector. Surg Endosc. 1995; 9(9): 1009-12.
- Moritz E. Laparoscopic fenestration of solitary giant cysts of the liver. Chirurg. 1991; 63(4): 379-80.
- Reggiani P., Antonelli B., Rossi G. Robotic surgery of the liver: Italian experience and review of the literature. Cancer Medical Science. 2013; 26(7): 358.
- Cherqui D, Husson E, Hammoud R, et al. Laparoscopic liver resections: a feasibility study in 30 patients. Ann Surg. 2000; 232: 753-62.
- Nguyen KT., Gamblin TC., Geller DA., World review of laparoscopic liver resection-2,804 patients. Annals of Surgery. 2009; 250(5): 831-41.
- Старков Ю.Г., Вишневский В.А. и cоавт. Результаты лапароскопических и традиционных операций при непаразитарных кистах печени. Анналы хирургической гепатологии. 2010; 15(2): 46-52.
- Gayet B., Cavaliere D., Vibert E., Perniceni T., Levard H., Denet C., Christidis C., Blain A., Mal F. Totally laparoscopic right hepatectomy. The American Journal of Surgery. 2007; 194(5): 685-9.
- Vibert E., Perniceni T., Levard H., Denet C., Shahri NK., Gayet B. Laparoscopic liver resection. British Journal of Surgery. 2006; 93(1): 67-72.
- Reich H., McGlynn F., DeCaprio J., Budin R. Laparoscopic excision of benign liver lesions. Obstetrics & Gynecology. 1991; 78(5): 956-8
- Chen DX, Wang SJ, Jiang YN, Yu MC, Fan JZ, Wang XQ. Robot-assisted gallbladder-preserving hepatectomy for treating S5 hepatoblastoma in a child: A case report and review of the literature. World J Clin Cases. 2019; 7(7): 872-80.
- Hyunhee Kwona, Ju Yeon Leeb, Yu Jeong Choa, Dae Yeon Kima, Seong Chul Kima, Jung-Man Namgoonga. How to safely perform laparoscopic liver resection for children: A case series of 19. Journal of Pediatric Surgery. 2019; 54(12): 2579–84.
- Taehoon Kim, Dae-Yeon Kim, Min Jeong Cho, Seong-Chul Kim, Jong Jin Seo, In-Koo Kim. Use of laparoscopic surgical resection for pediatric malignant solid tumors: a case. Surgical Endoscopy. 2011; 25 (5): 1484–8.
- Michelle A. Veenstra, Alan J. Koffron. Minimally-invasive liver resection in pediatric patients: initial experience and outcomes. HPB (Oxford). 2016; 18(6): 518-22.