Life-threatening thrombotic complications in a pediatric in the intensive care unit

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Abstract

Introduction. This article highlights the problem of thrombus formation in pediatric patients staying in ICU, namely, the problem of prevention and management of pulmonary embolism in children. Currently, there is a tendency to increasing pulmonary embolism occurrence in children, though there are no clear guidelines on the medicine dosage for the systemic thrombolytic therapy of pulmonary embolism in children and for the acute coronary syndrome in children with Kawasaki disease.
Clinical observations. The authors present two clinical cases from their practice when a successful management was obtained in children with life threatening thrombotic complications due to the applied systemic thrombolytic therapy.
Conclusion. The obtained success in the described clinical cases have resulted from a thorough analysis of ratios “risk-benefit” and “efficiency-safety”. But the authors conclude that further research work in this direction is still needed.

About the authors

A. E. Tsygankov

City Clinical Hospital No 40

Author for correspondence.
Email: tsygankovae1989@gmail.com
ORCID iD: 0000-0003-3600-2801

Alexander Е. Tsygankov, head of ICU department in infectious building

129301, Moscow

Russian Federation

I. I. Afukov

Filatov Children’s City Clinical Hospital; Pirogov Russian National Research Medical University

Email: fake@neicon.ru
ORCID iD: 0000-0001-9850-6779

123001, Moscow
117997, Moscow

Russian Federation

A. V. Vlasovа

Morozovskaya Children’s City Clinical Hospital

Email: fake@neicon.ru
ORCID iD: 0000-0001-5272-2070

119049, Moscow

Russian Federation

A. A. Glazyrina

Morozovskaya Children’s City Clinical Hospital

Email: fake@neicon.ru
ORCID iD: 0000-0002-2397-3484

119049, Moscow

Russian Federation

L. E. Larina

Morozovskaya Children’s City Clinical Hospital

Email: fake@neicon.ru
ORCID iD: 0000-0002-0735-7139

119049, Moscow

Russian Federation

R. S. Gitinovasov

City Clinical Hospital No 40

Email: fake@neicon.ru
ORCID iD: 0000-0002-9029-4852

129301, Moscow

Russian Federation

S. H. Kurbanova

Morozovskaya Children’s City Clinical Hospital

Email: fake@neicon.ru
ORCID iD: 0000-0003-0509-1055

119049, Moscow

Russian Federation

O. S. Chudina

Morozovskaya Children’s City Clinical Hospital

Email: fake@neicon.ru

119049, Moscow

Russian Federation

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