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Diffusion tensor imaging in trauma of the cervical spine in children
- Authors: Dmitrenko D.1, Akhadov T.1, Meshcheryakov S.1, Melnikov I.1, Bozhko O.1, Semenova Z.1, Ublinskiy M.1, Semenova N.1, Manzhurtsev A.1, Akhlebinina M.1, Kostikova T.1, Khusainova D.1
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Affiliations:
- Clinical and Research Institute of Emergency Pediatric Surgery and Trauma (CRIEPST)
- Issue: Vol 26, No 2 (2022)
- Section: ORIGINAL ARTICLES
- Submitted: 09.02.2022
- Accepted: 16.10.2022
- Published: 16.10.2022
- URL: https://jps-nmp.ru/jour/article/view/420
- DOI: https://doi.org/10.17816/ps420
- ID: 420
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Abstract
Introduction: The technique of diffusion tensor imaging (DTI) is widely used in brain research. However, in studies of the spinal cord, especially in pediatrics, the use of DTI is difficult: the small size of the spinal cord, which is characterized by a low signal-to-noise ratio, artifacts from respiration and pulsation of the heart and large vessels, and swallowing movements. Also, the EPI sequences used to obtain diffusion indices cause eddy current distortion.
Objective: to investigate changes in the parameters of DTI of the spinal cord in children with cervical spinal cord trauma.
Material and methods: 56 children aged 2 to 17 years with cervical spine injury (CSI) and 20 children who did not have CSI were examined using a Phillips Achieva 3 T magnetic resonance scanner. The protocol consisted of sagittal STIR, sagittal and axial T1- and T2WI SE, and axial DTI. For DTI, apparent diffusion coefficient (ADC), fractional anisotropy (FA), axial (AD) and radial (RD) diffusion coefficients were calculated.
Results: According to the ASIA criteria for injuries, out of 56 children, 29 (51%) had CSI with neurological complications, and 27 (49%) had no complications. The degree of neurological dysfunction A was in 13 patients, B - 3, C - 9, D - 4, E - 27 patients. The average values of the group of patients with were: ADC=0.74 ± 0.12*10−3 mm2/s−1, FA = 0.36 ± 0.07, BP=1.15 + 0.28*10−3 mm2/s−1, RD=0.52 + 0.32*10−3 mm2/s−1
Conclusion: DTI can detect changes beyond the limits of conventional MRI. Low ADC values in acute injury may indicate spinal cord injury and predict a negative functional outcome.
About the authors
Dmitriy Dmitrenko
Clinical and Research Institute of Emergency Pediatric Surgery and Trauma (CRIEPST)
Email: dmitrenich@mail.ru
ORCID iD: 0000-0003-1260-4509
Tolibdzhon Akhadov
Clinical and Research Institute of Emergency Pediatric Surgery and Trauma (CRIEPST)
Email: akhadov@mail.ru
ORCID iD: 0000-0002-3235-8854
Semen Meshcheryakov
Clinical and Research Institute of Emergency Pediatric Surgery and Trauma (CRIEPST)
Email: msaemon@rambler.ru
ORCID iD: 0000-0003-3701-4628
Ilya Melnikov
Clinical and Research Institute of Emergency Pediatric Surgery and Trauma (CRIEPST)
Email: iliamed@inbox.ru
ORCID iD: 0000-0002-2910-3711
Olga Bozhko
Clinical and Research Institute of Emergency Pediatric Surgery and Trauma (CRIEPST)
Email: bozhko_olga@mail.ru
ORCID iD: 0000-0002-4709-9461
Zhanna Semenova
Clinical and Research Institute of Emergency Pediatric Surgery and Trauma (CRIEPST)
Email: jseman@mail.ru
ORCID iD: 0000-0002-1610-2672
Maxim Ublinskiy
Clinical and Research Institute of Emergency Pediatric Surgery and Trauma (CRIEPST)
Author for correspondence.
Email: maxublinsk@mail.ru
ORCID iD: 0000-0002-4627-9874
Россия
Natalia Semenova
Clinical and Research Institute of Emergency Pediatric Surgery and Trauma (CRIEPST)
Email: nmr-semen@mail.ru
ORCID iD: 0000-0001-6641-0668
Andrei Manzhurtsev
Clinical and Research Institute of Emergency Pediatric Surgery and Trauma (CRIEPST)
Email: andrey.man.93@gmail.com
ORCID iD: 0000-0001-5022-9952
Maria Akhlebinina
Clinical and Research Institute of Emergency Pediatric Surgery and Trauma (CRIEPST)
Email: akhlebinina.m.i@gmail.com
ORCID iD: 0000-0001-9862-3609
Tatyana Kostikova
Clinical and Research Institute of Emergency Pediatric Surgery and Trauma (CRIEPST)
Email: kostikovatd@gmail.com
ORCID iD: 0000-0002-9103-9191
Daria Khusainova
Clinical and Research Institute of Emergency Pediatric Surgery and Trauma (CRIEPST)
Email: dsavina@yandex.ru
ORCID iD: 0000-0002-1698-0547
References
- Залетина А.В., Виссарионов С.В., Баиндурашвили А.Г., Садовой М.А., Соловьева К.С., Купцова О.А. Структура повреждений позвоночника у детей в регионах Российской Федерации. Хирургия позвоночника. 2017; 14(4): 52-60. doi: 10.14531/SS2017.4.52-60
- Ахадов Т.А., Панов В.О., Айхофф У. Травма спинного мозга и позвоночника и ее последствия. In: Магнитно-Резонансная Томография Спинного Мозга и Позвоночника. Москва; 2000:586-633.
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