A technique of combined laser photodestruction - for radical treatment of pyogenic granuloma in children



Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Introduction. Pyogenic granuloma is a benign vascular tumor-like formation on the skin having inflammatory etiology. It is often seen in childhood; its complications in the form of ulcerations and bleedings are met in about 7.5% of cases.

Material and methods. Over the past two years, 164 patients were operated on for pyogenic granulomas at the Clinical and Research Institute of Emergency Pediatric Surgery and Trauma (CRIEPST) in Moscow. 120 of them had bleedings in the anamnesis. Before surgery, all patients had ultrasound examination with color Doppler mapping (CDM) of their vascular formation. 137 children had planned surgeries under local anesthesia in an outpatient unit. 27 patients had bleeding from their pyogenic granulomas on the admission. On reaching hemostasis after conservative treatment, 21 of them had delayed surgeries; 6 children with severe bleeding, in who conservative treatment was ineffective, were operated urgently. All delayed surgeries were made under local anesthesia in an outpatient surgical room; urgent surgeries were performed under general anesthesia in a hospital surgical room.

A technique of combined laser photodestruction was applied in all 164 patients with pyogenic granulomas (invention priority dated May 11, 2022). Laser surgical device “IRE-Polyus” (Russia) with a wavelength of 0.97 urn, was used for this.

Results. Postoperative period in all patients was uneventful; complete healing of wound defect was seen on day 10±2. No recurrence or residual elements of the vascular formation were observed. After surgical treatment, good clinical and esthetic results were obtained in all 164 patients.

Conclusion. To prevent complications of pyogenic granulomas in children, surgical treatment with a technique of combined laser photodestruction is recommended. Moreover, the discussed technique has been developed with considerations of structural features of pyogenic granulomas. A technique of combined laser photodestruction allows to radically remove pathological tissues of pyogenic granuloma both in inpatient and outpatient settings and guarantees reliable hemostasis, thus providing good clinical and esthetic outcomes in pediatric patients.

About the authors

E. N. Gasanova

Research Institute of Emergency Pediatric Surgery and Traumatology" of the Department of Health of the City of Moscow

Author for correspondence.
Email: dr.ellada@mail.ru
ORCID iD: 0000-0001-7481-8874

Ella N. Gasanova - researcher of the Research Institute of Emergency Pediatric Surgery and Traumatology of the Department of Health of the City of Moscow.

Moscow 119180.

Россия

N. E. Gorbatova

Research Institute of Emergency Pediatric Surgery and Traumatology" of the Department of Health of the City of Moscow

Email: fake@neicon.ru
ORCID iD: 0000-0003-4949-7655

Moscow, 119180.

Россия

A. G. Dorofeev

Research Institute of Emergency Pediatric Surgery and Traumatology" of the Department of Health of the City of Moscow

Email: fake@neicon.ru
ORCID iD: 0000-0002-4776-9672

Moscow, 119180.

Россия

S. A. Zolotov

Research Institute of Emergency Pediatric Surgery and Traumatology" of the Department of Health of the City of Moscow

Email: fake@neicon.ru

Moscow, 119180.

Россия

I. V. Batunina

Research Institute of Emergency Pediatric Surgery and Traumatology" of the Department of Health of the City of Moscow

Email: fake@neicon.ru

Moscow, 119180.

Россия

A. V. Bryantsev

Research Institute of Emergency Pediatric Surgery and Traumatology" of the Department of Health of the City of Moscow

Email: fake@neicon.ru

Moscow, 119180.

Россия

References

  1. Wassef M., Blei F., Adams D. et al. Vascular anomalies classification: recommendations from the International Society for the Study of Vascular Anomalies. Pediatrics. 2015; 136(01): 203-14.
  2. Доманин А.А., Соловьева О.Н. Расчет диагностической значимости морфологических признаков пиогенной гранулемы и капиллярной гемангиомы. В кн.: Лечебно-диагностические, морфофункциональные и гуманитарные аспекты медицины. Тверь, 2011: 57-9.
  3. ISSVA classification for vascular anomalies (Approved at the 20th ISSVA Workshop, Melbourne, April 2014, last revision May 2018).
  4. Pagliai K.A., Cohen B.A. Pyogenic granuloma in children. Pediatr Dermatol. 2004 Jan-Feb; 21(1): 10-3.
  5. Cawson R.A., Binnie W.H., Speight P.M., Barrett A.W., Wright J.M. Lucas Pathology of Tumors of Oral Tissues. 5th ed. Missouri: Mosby; 1998: 252-4.
  6. Giblin A.V., Clover A.J., Athanassopoulos A., et al. Pyogenic granuloma -the quest for optimum treatment: an audit of treatment of 408 cases. J Plast Reconstr Aesthet Surg. 2007; 60(9): 1030-5.
  7. Park S.H., Lee J.H., Tak M.S., et al. A Research of Pyogenic Granuloma Genesis Factor With Immunohistochemical Analysis. Journal of Craniofacial Surgery. 2017; 28(8): 2068-72.
  8. Simmons B.J., Chen L., Hu S. Pyogenic granuloma association with isotretinoin treatment for acne. Australas J Dermatol. 2016; 57(4): 144-5.
  9. Lawley L.P., Cerimele F., Weiss S.W., et al. Expression of Wilms tumor 1 gene distinguishes vascular malformations from proliferative endothelial lesions. Arch Dermatol. 2005; 141: 1297-300.
  10. Small T.W., Bolender Z., Bueno C., et al. Wilms' tumor 1-associating protein regulates the proliferation of vascular smooth muscle cells. Circ Res. 2006; 99: 1338-46.
  11. Patrice S.J., Wiss K., Mulliken J.B. Pyogenic granuloma (lobular capillary hemangioma): a clinicopathologic study of 178 cases. Pediatr Dermatol. 1991 Dec; 8(4): 267-76.
  12. Al-Thunayan A., Al-Rehaili M., Al-Meshal O., Al-Qattan M.M. Bacillary angiomatosis presenting as a pyogenic granuloma of the hand in an otherwise apparently healthy patient. Ann Plast Surg. 2013 Jun; 70(6): 652-3.
  13. Ramirez-Amador V., Martinez-Mata G., Gonzalez-Ramirez I., Anaya Saavedra G., De Almeida O.P. Clinical, histological and immunohistochemical findings in oral Kaposi's sarcoma in a series of Mexican AIDS patients. Comparative study. J Oral Pathol Med. 2009; 38: 328-33.
  14. Krishnapillai R., Punnoose K., Angadi P.V., Koneru A. Oral pyogenic granuloma - a review of 215 cases in a South Indian Teaching Hospital, Karnataka, over a period of 20 years. OralMaxillofacSurg. 2012; 16: 305-9.
  15. Taira J.W., Hill T.L., Everett M.A. Lobular capillary hemangioma (pyogenic granuloma) with satellitosis. J Am Acad Dermatol. 1992; 27: 297-300.
  16. Ефанова Е.Н., Русак Ю.Э., Васильева Е.А. и др. Пиогенная гранулема как междисциплинарная проблема. Лечащий врач. 2017; 8: 61-3.
  17. Шахно Е.А. Физические предпосылки применения лазера в медицине. Учебное пособие. Санкт-Петербург: НИУ ИТМО; 2012.
  18. Tanzi E.L., Lupton J.R., Alster T.S. Lasers in dermatology: four decades of progress. J Am Acad Dermatol. 2003; 49(1): 1-31.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c)

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies