The efficacy of water-soluble contrast media in the treatment of meconium ileus in preterm neonates.



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Abstract

Background. Meconium ileus presents a serious challenge in neonatology, requiring timely diagnosis and effective treatment. The application of new conservative therapy methods can improve outcomes and reduce the need for surgical intervention, especially in newborns.

 

Clinical case description. This case study presents a preterm newborn boy with meconium ileus diagnosed on the second day of life. The use of a water-soluble contrast based on resistant starch and iopromide led to the resolution of intestinal obstruction without the need for surgical intervention. The contrast passage was conducted over 24 hours, after which effective spontaneous stool appeared. Enteral insufficiency was resolved. The child was discharged home on the 14th day of life with positive weight dynamics. An irrigography showed no evidence of Hirschsprung's disease.

 

Conclusion. The use of water-soluble contrast based on resistant starch and iopromide can be an effective method of conservative treatment for meconium ileus in newborns, allowing to avoid surgical intervention and associated risks. This method requires further study to evaluate long-term safety and effectiveness.

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About the authors

F. M. Shvalev

Children's Regional Clinical Hospital, Yekaterinburg, Russia;
Ural State Medical University, Regional Center, Yekaterinburg, Russia;

Author for correspondence.
Email: aesthetic@list.ru
ORCID iD: 0009-0005-0709-2213
SPIN-code: 6488-3900

Pediatric Surgeon, Surgical Department No. 2

Россия, 620149, Russia, Yekaterinburg, S. Deryabina St., 32; 620028, Russia, Yekaterinburg, Repina St., 3;

N. A. Tsap

Ural State Medical University, Regional Center, Yekaterinburg, Russia;

Email: tsapna-ekat@rambler.ru
ORCID iD: 0000-0001-9050-3629
SPIN-code: 7466-8731

Head of the Department of Pediatric Surgery MD, Professor;
Россия, 620028, Russia, Yekaterinburg, Repina St., 3;

V. B. Chudakov

Children's Regional Clinical Hospital, Yekaterinburg, Russia;

Email: vb.chudakov@gmail.com
ORCID iD: 0000-0002-4306-1378
SPIN-code: 5206-0649

Head of Surgical Department No. 2, Pediatric Surgeon

Россия, 620149, Russia, Yekaterinburg, S. Deryabina St., 32;

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Copyright (c) Shvalev F.M., Tsap N.A., Chudakov V.B.

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