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Vol 25, No 3 (2021)

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ANNIVERSARY

Maya Konstantinovna Bukhrashvili (to the 90th birthday anniversary)

Abstract

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Russian Journal of Pediatric Surgery. 2021;25(3):150-152
pages 150-152 views

ORIGINAL ARTICLES

Multiple intestinal anastomosis in newborns and infants

Kozlov Y.A., Mochalov M.N., Kovalkov K.A., Poloyan S.S., Baradieva P.Z., Zvonkov D.A., Ochirov C.B., Cheremnov V.S., Stankeev V.A., Rozhanski A.P., Kozlov S.Y., Sandakov Y.P.

Abstract

Introduction. The present trial systematizes data, taken from one surgical center as an example, on treating patients with intestinal atresia and necrotizing enterocolitis with multiple intestinal anastomoses.

Material and methods. The trial is a retrospective review on the treatment of 13 newborn infants who since 2010 have been put multiple intestinal anastomoses; the treatment was approved by the Hospital Ethics Committee. The average gestational age of patients was 31.2 weeks. The average age at the time of surgery – 7,9 days. Average weight - 2007 grams. The average number of anastomoses was 3.7 (range: 2-7). The average length of remained small intestine after the second surgery was 67.4 cm (range: 12-120 cm). No other surgical procedures, including gastrostomy or enterostomy, were performed. In all cases, surgical intervention ended with hermetic suturing of the abdominal cavity. Among them, there were 6 patients with the multifocal form of necrotizing enterocolitis; 6 patients had type IV atresia of the small intestine; 1 patient had the Ladd’s syndrome. Connection of intestinal segments was made by constructing several “end-to-end” anastomoses, double-row precision seam with PDS II 7/0 suture.

Results. In the postoperative period, complications associated with anastomosis construction, such as leakage and narrowing, were not recorded. Transit function of the gastrointestinal tract restored on day 4, on average, after the surgery (range: 2-6 days). There were no early lethal outcomes within the first 28 days after the surgery which were associated with the surgery. 2 patients with short bowel syndrome (remained small intestine was 12 and 25 cm) and multivisceral disorders died on day 72 and 64 after the surgery. Survived patients were transferred to full enteral feeding in 56 days, in average, after the second surgery (range - 15-120 days).

Conclusion. In our study, we have demonstrated potentials of a new surgical approach: one-stage formation of multiple intestinal anastomoses in case of multiple intestinal atresias as well as in case of multifocal forms of necrotizing enterocolitis. Maintaining the bowel length with multiple bowel anastomoses is very important factor for better survival of patients with the short bowel syndrome.  

Russian Journal of Pediatric Surgery. 2021;25(3):153-157
pages 153-157 views

Outcomes of surgical treatment of neonates with intestinal stomas in a regional perinatal center

Ivanov S.D., Slizovskij G.V., Balaganskiy D.A., Pogorelko V.G., Yushmanova A.B.

Abstract

Introduction. Emergency intestinal surgeries in neonates can lead to stoma formation. Indications for stoming, associated complications and ways to prevent them are being actively discussed. The aim of this study was to analyze results of surgical treatment of neonates with intestinal stomas in a perinatal center for the last 10 years.

Material and methods. 81 children with intestinal obstruction (32), necrotizing enterocolitis (27), meconium ileus (14) and others abdominal pathologies (8) were included into the study. Statistical processing was carried out using the SPSS v.26 package; differences were significant at p-value ≤0.05. Complications were assessed with the Clavien-Dindo Сlassification (CDC).

Results. There were 59 premature infants (72.8%); 32 had body weight below 1000 grams (54.2%). Initially performed: 15 (18.5%) colostomies, 49 (60.5%) enterostomies, 17 (21%) T-anastomoses. A compression clip was put in six children with double-barreled ileostomies. Complications were the following: prolapse (12.3%), skin excoriation (43.2%), bleeding (19.8%), large losses of intestinal chyme (17.3%), liver failure (19.8%), sepsis (17.3%), wound dehiscence (6.2%), adhesive obstruction (16%), necrosis (9.9%) and stenosis (7.4%). 16 (19.7%) patients had no complications. 28 (43%) patients had complications by CDC of grade

Conclusion. If a neonate patient has contraindications to primary anastomosing, double-barreled enterostomy with a compression clip is a safe alternative to it. The enterostomy technique in premature newborns does not increase the rate of complications and mortality. Skin excoriation, increased bleeding from the stoma, and liver failure are most common in neonates with enterostomy.

Russian Journal of Pediatric Surgery. 2021;25(3):158-164
pages 158-164 views

Minilaparotomy in the treatment of choledochal malformations in children

Razumovskiy A.Y., Mitupov Z.B., Kulikova N.V., Stepanenko N.S., Zadvernyuk A.S., Titova E.A., Shubin N.V.

Abstract

Introduction. The article presents the analysis of surgical treatment of children with choledochal malformations (CM) with mini-laparotomy and laparoscopy techniques.

Purpose. The aim of the study is to improve outcomes of surgical treatment of choledochal malformations in children.

Material and methods. For the last ten years (January 2010 - May 2020), 84 children with choledochal malformations (CM) (n = 84) were operated on with different surgical techniques in our hospitals. Group 1 - patients who had Roux-en-Y hepaticojejunoanastomosis (RYHJ, n = 68, 81%); Group 2 - patients who had hepaticoduodenoanastomosis (HD, n = 16, 19%). The authors compared outcomes because Roux-en-Y hepaticojejunostomosis and hepaticoduodenanastomosis were formed under mini-laparotomic (ML) and laparoscopic (LS) accesses. Surgical time, short-term and long-term postoperative outcomes were assessed.

Results. The groups were comparable in gender, age, clinical manifestations, CM complications before surgery, comorbidities (p > 0.05). A statistically significant (p = 0.0000001, Mann–Whitney U-test) decrease in the surgical time was revealed when using mini-laparotomy access. Independent defecation appeared 3 times faster in the subgroup with mini-laparotomy and Roux-en-Y hepaticojejunostomy (ML RYHJ) than in the subgroup of laparoscopic Roux-en-Y hepaticojejunostomy (LS RYHJ) (p = 0.033, Mann–Whitney U-test), mainly due to early enteral loading in the first subgroup (on 0-1 postoperative day). Long-term postoperative outcomes in laparoscopic subgroups revealed a statistically insignificant (p> 0.05) prevalence of 4 anastomotic stenosis requiring repeated surgical interventions. Good outcomes were seen in 90% of patients after ML RYHJ (p = 0.002, Pearson’s Chi-square with Yates’ correction) versus 52.6% after LS RYHJ.

Conclusion. Currently, laparoscopy is not a method of choice in children with CM due to the development of short-term and long-term postoperative complications. Minilaparotomy gives promising results in pediatric CM and can be “a gold standard” in the treatment of children with this pathology.

Russian Journal of Pediatric Surgery. 2021;25(3):165-173
pages 165-173 views

Prospects for improving primary health care to children with thermal injuries

Oborkina D.S., Dolotova D.D., Butkevich L.I.

Abstract

Introduction. Burn injury in children has been and remains one of the most significant cause of disability and death in the world. An important aspect in relation to the prognosis and course of the wound process is the quality of the first aid provided at the prehospital stage. Untimely diagnosed shock, inadequately prescribed anesthesia, attempts to perform surgical treatment of wounds at the site of the accident can fatally affect the prognosis of the disease.

Material and methods. A retrospective analysis of medical documentation of 328 children who were treated at the burn center from 2016 to 2019 was made. Selection criteria were: arrival to the center by ambulance, shock, transfer to ICU. To analyze actions performed in the prehospital stage, a number of parameters were identified: diagnosis, length of transportation, specialists in the ambulance team, TBSA (total burn surface area), thermal inhalation lesion, and others.

Results. The overwhelming majority of errors refer to diagnostics: shock (94.5%), incorrect TBSA assessment (63.7%), inadequate pain relief (61.9%), etc. A reliable correlation was revealed between ineffective analgesia and incorrect assessment of thermal lesion area. Life-threatening conditions develop in case of incorrect primary surgical treatment of wounds, incorrect vascular puncture, tracheal intubation, etc.

Conclusions. The revealed difficulties in providing the primary medical aid to burnt patients at the site of accident require the development of a clearer and more understandable algorithm for medical personnel who provide the first aid to children with burns.  

Russian Journal of Pediatric Surgery. 2021;25(3):174-178
pages 174-178 views

REVIEWS

Surgical treatment of stable foci of the osteochondritis dissecans in children: a systematic review

Semenov A.V., Kukueva D.M., Lipkin Y.G., Isaev I.N., Koroteev V.V., Tarasov N.I., Lozovaya Y.I., Vybornov D.Y.

Abstract

Introduction. The osteochondritis dissecans (OCD) is a pathologic condition of osteochondral tissue predominantly in the femoral condyles, which is met most often in adolescents and which can lead to the formation of early arthrosis in the knee joint in the remote time. By modern concepts, stable OCD foci are the foci with intact articular cartilage without the risk of migration into the joint cavity. To date, there are very few studies in the world literature on the treatment of early stages of osteochondrosis dissecans.

Material and methods. Two independent researchers have carried out a systematic review of literature sources (2000-2020 ) using Pubmed, Medline and GoogleScholar. 9 publications were selected for data analysis out of 5184 publications after the qualitative assessment by the Yang scale and the obtained consensus in disputable situations.

Results. Statistical analysis of the obtained data with the Statistica program revealed that the average rate of OCD foci healing was seen in 86.7% (from 70.6 to 100%). The most effective outcomes were in the group of antegrade drilling (95.3% of healed foci), then in the group with biodegradable implants fixation (88.5%), then the group of antegrade drilling with the introduction of bone marrow aspirate concentrate (BMAC) - 76.9%, and then the retrograde drilling - 76.8%.

Conclusion. The analysis performed have shown a significant heterogeneity in data reporting, different methods for diagnosing osteochondritis dissecans, different approaches to healing assessment as well as a small number of children in samples what determined the lack of statistical significance between different options of surgical treatment (p = 0.27). Carefully planned trials with a proper design, standardized techniques for healing assessment and time of their application as well as the assessment of comparison groups and of all other necessary factors affecting lesion healing are needed.

Russian Journal of Pediatric Surgery. 2021;25(3):179-185
pages 179-185 views

Rectal prolapse in children. Causes, diagnostics, treatment (a literature review)

Pimenova E.S., Korolev G.A.

Abstract

Introduction. Rectal prolapse is evagination of the rectal wall outside the anal opening. It can be full-thickness, partial thickness or mucosal. Rectal prolapse is most often met in children from 1 to 4 years of age. This is due to their anatomical features: vertical position of the rectum (open anorectal angle), mobile sigmoid colon, increased mobility of the rectal mucous. Chronic constipation plays an important role in evagination as well as infection, parasitic diseases and cystic fibrosis.

Material and methods. Literature searches were done in Scopus, PubMed, Google Scolar and eLibrary databases.

Results. Diagnostics includes disease history and physical examination. It is important to differentiate rectal prolapse from hemorrhoids and prolapsing rectal polyps. Photos taken by parents at the moment of prolapse can benefit in making a rapid and correct diagnosis as at the moment of examination the prolapse has very often been corrected. Currently, there are three basic approaches for rectal prolapse care: conservative, sclerotherapy and surgical. The conservative treatment is aimed to reduce the prolapse and to treat the basic disease. Sclerotherapy is the injection of the preparation which causes local inflammation and fibrosis. The injection is made into the pararectal space. If the conservative treatment is ineffective and the patient suffers of frequent prolapses, strangulation, mucous bleedings, than surgical treatment may be indicated for children older than 4.

Conclusion. The meta-analysis, performed recently, has demonstrated that conservative treatment is recommended for children before 4 because spontaneous prolapse correction is often seen in this age group. 70% ethyl alcohol is very effective as the sclerosant. Surgical interventions in case of the rectal prolapse are various; open and laparoscopic rectopexy is considered the most effective one. In some cases, rectum fixation with mesh is indicated. Currently, there is no any technique for rectal prolapse treatment which could guarantee no recurrences. Curative tactics is always individual.

Russian Journal of Pediatric Surgery. 2021;25(3):186-191
pages 186-191 views

CASE REPORT

Intermittent intestinal intussusception in patients with mesenteric lymphadenitis in the ileocecal angle

Karaseva O.V., Golikov D.E., Kharitonova A.Y., Gorelik A.L., Timofeeva A.V., Batunina I.V., Yanyushkina O.G., Kislyakov A.N.

Abstract

Introduction. At present, lymphadenopathy – as a cause of idiopathic intestinal intussusception in little children - comes to the fore. However, intestinal intussusception in case of destructive mesenteric lymphadenitis in combination with lymphoid hyperplasia of the ileocecal angle ( what does not exclude lymphoma intraoperatively) is extremely rare in clinical practice.

Purpose. To present a therapeutic and diagnostic algorithm in intestinal intussusception which was caused by the “volumetric“ abdominal lymphadenopathy.

Case Report. A 3-year-old boy was admitted by the ambulance with recurrent abdominal pain, single episode of vomiting and no stool for 4 days. The ultrasound examination revealed intermittent ileocecal intussusception. The risk factor which had triggered the disease was an acute respiratory viral infection complicated with purulent mesenteric lymphadenitis and lymphoid hyperplasia with ulcerative lesions of the mucous membrane in the ileocecal junction. Laparoscopic desinvagination with lymph node removal and colonoscopy with ladder biopsy were performed. A differential diagnostics of nonspecific lymphadenopathy, Burkitt’s lymphoma and Crohn’s disease was made. Immunohistological examination intraoperatively was made; examination of the biopsy material excluded tumor and inflammatory bowel disease (IBD). The inflammatory process regressed under conservative therapy (antibacterial, anti-inflammatory and antispasmolytic) ; there were no any recurrent intussusception episodes within one-year follow-up.

Conclusion. Successive ultrasound, laparoscopic and colonoscopic examinations followed by the immunohistological analysis of intraoperative and biopsy material allowed to put a correct diagnosis and, thereby, to minimize surgical aggression in ileocecal intussusception which was accompanied by volumetric lymphadenopathy.

Russian Journal of Pediatric Surgery. 2021;25(3):192-197
pages 192-197 views

Pyloric atresia: authors’ clinical experience and literature review

Podkamenev A.V., Syrtsova A.R., Ti R.A., Kuzminykh S.V., Dvoreckij V.S., Myznikova I.V., Veretennikova A.A., Murashova O.A.

Abstract

Introduction. Congenital pyloric atresia is a rare malformation of the stomach outlet which amounts to about 1% of all atresias in the gastrointestinal tract. The gastric outlet atresia may be either isolated or combined with other abnormalities.

Material and methods. There are few publications on the surgical treatment of pyloric atresia with extraluminal and intraluminal endoscopic interventions; however, at present information about it is not enough to assess their effectiveness and safety in young children. In literature, one can also find only few detailed reviews on clinical observations of pyloric atresia; most of which describe anatomical type I. Membranectomy and pyloroplasty are used for surgical treatment of pyloric atresia of type I. Surgery for pyloric atresias of types II and III which includes the resection in atresia zone and the formation of anastomosis between the stomach and duodenum causes complications due to the duodeno-gastric reflux in postoperative period. To prevent these complications, there is a surgical technique which was first described by A. Dessanti, et al. and later was modified and detailed by S. Yokoyama. This article is a literature overview on the topic and authors’ own experience in treating pyloric atresia of type II in 2 patients and of type I in one 1 patient.

Conclusion. The choice of surgical approach depends on the anatomical type of pyloric atresia. Currently, there is no any unified approach to the surgical treatment of atresia of types II and III. Membranectomy and gastroduodenoanastomosis seem to be the most appropriate surgical techniques to correct this abnormality what has been confirmed by our preliminary findings.  

Russian Journal of Pediatric Surgery. 2021;25(3):198-204
pages 198-204 views

Problems with diagnostics in newborn having the combined pathology of gastric membrane and intestinal atresia

Gumerov A.A., Galimov I.I., Nafikova R.A., Neudachin A.E., Miniakhmetov A.A.

Abstract

Introduction. Congenital malformations of the gastrointestinal tract (GIT) are one of the most common causes of intestinal obstruction and require urgent surgical care in the neonatal period. In the overall structure of GIT, gastrointestinal defects amount up to 25%. Duodenal atresia accounts for 1 case per 7,000–10,000 newborns; jejunal and ileac atresia - 1 case per 1,000–3,000 newborns. Often, the diagnosis is made antenatal. In most cases, diagnostics of intestinal atresia is not difficult, and treatment is carried out in a timely manner. However, in rare cases, intestinal atresia is combined with other congenital malformations in GIT, for example, stomach or duodenum webs. In such a case, if during the atresia surgical correction, a gastric membrane was not suspected, then in the postoperative period there may be problems with treatment requiring additional diagnostics. As a result, web surgical correction is postponed, and the child’s general state can worsen.

Material and methods. The authors discuss two cases and their treatment in newborn children who had membranes in their stomach and duodenum combined with the intestinal atresia.

Results. The authors also discuss problems which they faced in the diagnostics and treatment. They give their recommendations how to improve diagnostics in children with combined congenital malformations in their gastro-intestinal tract.

Conclusion. The full range of diagnostic measures before surgery and a thorough revision of abdominal organs during surgery are key issues in children with gastric and duodenal abnormalities. Undiagnosed and undetected malformations during the first surgical intervention may require a repeated surgical intervention which can worsen the child’s general state.  

Russian Journal of Pediatric Surgery. 2021;25(3):205-208
pages 205-208 views

The colon membrane as a cause of large bowel obstruction in a child of 11-month old: a case report

Smirnov A.N., Кholostova V.V., Voyna S.A., Gladeeva V.S., Amanova M.A., Kulevich B.O.

Abstract

Introduction. Colon atresia is a rare form of congenital bowel obstruction. In scientific literature, there are isolated publications devoted to colon atresia, and only some authors discuss the membranous form of atresia.

Material and methods. The article describes a rare clinical case of an incomplete colon membrane in an infant. At the age of 11 months, the child developed symptoms of acute intestinal obstruction. Irrigography was performed; Hirschsprung’s disease was suspected. At the first stage, the child was taken a floor-by-floor biopsy of the colon, and an ileostomy was put. Visually, Hirschsprung’s disease seemed to be present; however, histological examination turned aside this diagnosis. Given this, the colon membrane was suspected. Partial resection of the altered part of the sigmoid colon was performed with good clinical effect. Histological examination revealed an incomplete serous-muscular membrane of the colon.

Conclusion. Colon atresia is a rare disease that presents a serious problem for diagnosis and treatment. Preoperative morphological verification of the diagnosis is important, even in case when Hirschsprung’s disease seems obvious. Preoperative diagnostics is important because surgical tactics may be considerably different in colon local lesions. 

Russian Journal of Pediatric Surgery. 2021;25(3):209-213
pages 209-213 views

Multiple foreign bodies in the gastrointestinal tract of a 13-year-old child

Nalbandyan R.T., Kapustin V.A., Medinskiy P.V., Bagaev V.G., Lvova E.A., Gromova A.A.

Abstract

Introduction. Foreign bodies in the gastrointestinal tract are various objects of organic and inorganic origin, which are swallowed - not as food - either accidentally or intentionally. The article describes a clinical case of a 13-year-old child with multiple foreign bodies in his gastrointestinal tract which could cause serious complications, such as: perforation of hollow organs, peritonitis, intestinal obstruction, internal bleeding. By statistics, every fourth patient of the conscious age with foreign bodies in the gastrointestinal tract can potentially have problems in the neuropsychic sphere.

Material and methods. A 13-year-old boy was admitted to the Clinical and Research Institute of Emergency Pediatric Surgery and Trauma (CRIEPST) with nausea, repeated vomiting after each meal and water drinking. The careful anamnesis revealed that before the boy’s state deteriorated, he had swallowed a large number of magnets and metal objects within a short period of time. X-rays examination found multiple foreign bodies in his gastrointestinal tract. They were removed during esophagogastroduodenoscopy (EGDS) and surgical intervention.

Results. The plain-film X-ray examination of the abdomen in the projection of the stomach revealed a radiopaque group of foreign bodies of a rounded shape as a conglomerate. At FEGDS, 54 objects were removed: 4 metal balls up to 0.5 cm in diameter, 47 round magnets up to 1.5 cm in diameter, a metal chain and two screws. During laparotomy and gastrotomy 99 foreign bodies were removed: 82 magnet balls 0.5 cm in size, 16 metal balls 1.5 cm in size, 1 bolt. The postoperative period was uneventful. The child was discharged on the 12 th day after surgery in the satisfactory state.

Conclusion. Due to timely diagnostics and proper curative tactics, multiple foreign bodies were revealed and removed from the child’s stomach endoscopically and surgically within a short period of time. A correctly chosen curative tactics resulted in a complete recovery of the patient without complications on the 12th hospitalization day.

Russian Journal of Pediatric Surgery. 2021;25(3):214-219
pages 214-219 views

Torsion of the uterine appendages in a 12-year-old girl

Bebenina A.A., Chundokova M.A., Golovanev M.A.

Abstract

Introduction. The uterine appendage torsion (UAT) is an urgent pathology accompanied by a painful abdominal syndrome and requiring urgent diagnostic and therapeutic measures. In childhood, UAT develops mainly due to organic causes and due to the specific location of internal organs in children. The literature data on organ-preserving surgeries in the long-lasting UAT is very controversial and dubious. There are no objective criteria for assessing ovarian viability after detorsion what impacts the selection of surgical intervention tactics - unjustified adnexectomy may be performed.

Clinical case. Girl P., 12 years old, was admitted to the hospital with a clinical picture of long-lasting torsion of the uterus appendages. Right uterine appendages were detorsed. The child was under observation. In two years, laparoscopic appendectomy was performed for chronic appendicitis. When examining pelvic organs, the right ovary was found reduced in size compared to the left one; there were no macroscopically visible changes; single follicles were visualized in it; the fallopian tube was not changed.

Conclusion. A painful sensation before surgery indicates that the uterus appendages are viable; if there is no abdominal pain, necrosis of the ovary and fallopian tube may be suspected. A surgical tactics is chosen on making a comprehensive analysis of clinical and instrumental findings.

Russian Journal of Pediatric Surgery. 2021;25(3):220-223
pages 220-223 views

HISTORY OF PEDIATRIC SURGERY. JUBILEES

Dmitrii Anatolevich Morozov (to the 50th birthday anniversary)

Abstract

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Russian Journal of Pediatric Surgery. 2021;25(3):224-225
pages 224-225 views

Sergei Viktorovich Minaev (to the 50th birthday anniversary)

Abstract

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Russian Journal of Pediatric Surgery. 2021;25(3):226
pages 226 views

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