A clinical case of surgical treatment of a large kidney cyst in a 9-year-old girl with autosomal dominant polycystic kidney disease

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BACKGROUND: Autosomal dominant polycystic kidney disease is currently the most common inherited form of cystic kidney disease, the frequency of which is about 1 per 400–1000 newborns, what makes the problem relevant. Its progressive course in patients with polycystic disease is primarily associated with the ischemic component, the severity of which depends on the number, location and size of cysts. Arterial hypertension, which is an autosomal dominant polycystic kidney disease complication, plays a leading role in renal failure progression. Given the current lack of specific treatment, the main therapeutic goal is to prevent complications, postpone the development of renal failure. Therefore, if there are large and giant cysts, surgical treatment is an effective modality and should be performed in a timely manner.

CLINICAL CASE DESCRIPTION: The authors present a clinical case of a successful endovideosurgical cyst excision in a -year-old patient with a giant cyst in the right kidney, autosomal dominant polycystic disease, and hypertension of renal genesis.

Endovideosurgical cystectomy in the patient with autosomal dominant polycystic kidney disease has become an important pathogenetic link in the treatment of this pathology. Currently, the patient is under dynamic follow-up for more than one year. During the follow-up period, the patient demonstrates relief of urinary syndrome in the form of disappeared haematuria, stabilization of albuminuria indices, improvement of blood flow parameters in the renal parenchyma, as well as stabilization of arterial pressure.

CONCLUSION: The given clinical example demonstrates that reasonable surgical intervention with the choice of a rational method of access, taking into account the anatomical localization and size of the cystic formation, allowed to obtain a good result in the form of stabilization of renal hemodynamics in a patient with autosomal dominant polycystic kidney disease.

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作者简介

Anna Oganisyan

V.F. Voyno-Yasenetsky Scientific and Practical Center of Specialized Medical Care for Children

编辑信件的主要联系方式.
Email: oganisyanaa@yandex.ru
ORCID iD: 0000-0002-5495-4315
SPIN 代码: 3707-2382
俄罗斯联邦, Moscow

Artem Vrublevskiy

V.F. Voyno-Yasenetsky Scientific and Practical Center of Specialized Medical Care for Children

Email: a.s.vrublevskij@yandex.ru
ORCID iD: 0000-0001-8550-8636
SPIN 代码: 3041-3173
俄罗斯联邦, Moscow

Revaz Valiev

V.F. Voyno-Yasenetsky Scientific and Practical Center of Specialized Medical Care for Children

Email: rvaliev.dr@yandex.ru
ORCID iD: 0000-0003-1805-9169
SPIN 代码: 9460-0920
俄罗斯联邦, Moscow

Filipp Turov

V.F. Voyno-Yasenetsky Scientific and Practical Center of Specialized Medical Care for Children

Email: filipp_100@mail.ru
ORCID iD: 0000-0002-9301-7586
SPIN 代码: 6683-1547
俄罗斯联邦, Moscow

Mamay Khanov

V.F. Voyno-Yasenetsky Scientific and Practical Center of Specialized Medical Care for Children

Email: 8_00@mail.ru
ORCID iD: 0000-0003-3354-5018
SPIN 代码: 8968-3164
俄罗斯联邦, Moscow

Sergey Vrublevskiy

V.F. Voyno-Yasenetsky Scientific and Practical Center of Specialized Medical Care for Children; Russian National Research Medical University named after N.I. Pirogov

Email: s.g.vrublevskiy@yandex.ru
ORCID iD: 0000-0001-9400-7673
SPIN 代码: 6535-2570
俄罗斯联邦, Moscow; Moscow

Elena Vrublevskaya

V.F. Voyno-Yasenetsky Scientific and Practical Center of Specialized Medical Care for Children; Russian National Research Medical University named after N.I. Pirogov

Email: vrublevskaj@mail.ru
ORCID iD: 0000-0001-7312-5945
SPIN 代码: 4003-1783
俄罗斯联邦, Moscow; Moscow

参考

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2. Fig. 1. Ultrasound examination of patient K., 10 years old: a — autosomal dominant polycystic kidney disease in B-mode; b — cyst of the middle segment of the right kidney.

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3. Fig. 2. Patient K., laparoscopic picture: a — cyst of the right kidney is visualized; b — puncture of the cyst with evacuation of its content and subsequent sclerosing.

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4. Fig. 3. Patient K. Laparoscopic picture, plasma ablation of the cyst inner lining.

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5. Fig. 4. Ultrasound examination of patient K., autosomal dominant polycystic kidney disease, result one month after endosurgical fenestration of the cyst: a — B-mode with dopplerography; b — В-mode.

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版权所有 © Oganisyan A.A., Vrublevskiy A.S., Valiev R.Y., Turov F.O., Khanov M.M., Vrublevskiy S.G., Vrublevskaya E.N., 2023

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