A clinical case of surgical treatment of a large kidney cyst in a 9-year-old girl with autosomal dominant polycystic kidney disease
- Authors: Oganisyan A.A.1, Vrublevskiy A.S.1, Valiev R.Y.1, Turov F.O.1, Khanov M.M.1, Vrublevskiy S.G.1,2, Vrublevskaya E.N.1,2
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Affiliations:
- V.F. Voyno-Yasenetsky Scientific and Practical Center of Specialized Medical Care for Children
- Russian National Research Medical University named after N.I. Pirogov
- Issue: Vol 27, No 6 (2023)
- Pages: 462-469
- Section: CLINICAL OBSERVATIONS
- Submitted: 22.01.2024
- Accepted: 22.01.2024
- Published: 26.12.2023
- URL: https://jps-nmp.ru/jour/article/view/783
- DOI: https://doi.org/10.17816/ps783
- ID: 783
Cite item
Abstract
BACKGROUND: Autosomal dominant polycystic kidney disease is currently the most common inherited form of cystic kidney disease, the frequency of which is about 1 per 400–1000 newborns, what makes the problem relevant. Its progressive course in patients with polycystic disease is primarily associated with the ischemic component, the severity of which depends on the number, location and size of cysts. Arterial hypertension, which is an autosomal dominant polycystic kidney disease complication, plays a leading role in renal failure progression. Given the current lack of specific treatment, the main therapeutic goal is to prevent complications, postpone the development of renal failure. Therefore, if there are large and giant cysts, surgical treatment is an effective modality and should be performed in a timely manner.
CLINICAL CASE DESCRIPTION: The authors present a clinical case of a successful endovideosurgical cyst excision in a -year-old patient with a giant cyst in the right kidney, autosomal dominant polycystic disease, and hypertension of renal genesis.
Endovideosurgical cystectomy in the patient with autosomal dominant polycystic kidney disease has become an important pathogenetic link in the treatment of this pathology. Currently, the patient is under dynamic follow-up for more than one year. During the follow-up period, the patient demonstrates relief of urinary syndrome in the form of disappeared haematuria, stabilization of albuminuria indices, improvement of blood flow parameters in the renal parenchyma, as well as stabilization of arterial pressure.
CONCLUSION: The given clinical example demonstrates that reasonable surgical intervention with the choice of a rational method of access, taking into account the anatomical localization and size of the cystic formation, allowed to obtain a good result in the form of stabilization of renal hemodynamics in a patient with autosomal dominant polycystic kidney disease.
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About the authors
Anna A. Oganisyan
V.F. Voyno-Yasenetsky Scientific and Practical Center of Specialized Medical Care for Children
Author for correspondence.
Email: oganisyanaa@yandex.ru
ORCID iD: 0000-0002-5495-4315
SPIN-code: 3707-2382
Россия, Moscow
Artem S. Vrublevskiy
V.F. Voyno-Yasenetsky Scientific and Practical Center of Specialized Medical Care for Children
Email: a.s.vrublevskij@yandex.ru
ORCID iD: 0000-0001-8550-8636
SPIN-code: 3041-3173
Россия, Moscow
Revaz Y. Valiev
V.F. Voyno-Yasenetsky Scientific and Practical Center of Specialized Medical Care for Children
Email: rvaliev.dr@yandex.ru
ORCID iD: 0000-0003-1805-9169
SPIN-code: 9460-0920
Россия, Moscow
Filipp O. Turov
V.F. Voyno-Yasenetsky Scientific and Practical Center of Specialized Medical Care for Children
Email: filipp_100@mail.ru
ORCID iD: 0000-0002-9301-7586
SPIN-code: 6683-1547
Россия, Moscow
Mamay M. Khanov
V.F. Voyno-Yasenetsky Scientific and Practical Center of Specialized Medical Care for Children
Email: 8_00@mail.ru
ORCID iD: 0000-0003-3354-5018
SPIN-code: 8968-3164
Россия, Moscow
Sergey G. Vrublevskiy
V.F. Voyno-Yasenetsky Scientific and Practical Center of Specialized Medical Care for Children; Russian National Research Medical University named after N.I. Pirogov
Email: s.g.vrublevskiy@yandex.ru
ORCID iD: 0000-0001-9400-7673
SPIN-code: 6535-2570
Россия, Moscow; Moscow
Elena N. Vrublevskaya
V.F. Voyno-Yasenetsky Scientific and Practical Center of Specialized Medical Care for Children; Russian National Research Medical University named after N.I. Pirogov
Email: vrublevskaj@mail.ru
ORCID iD: 0000-0001-7312-5945
SPIN-code: 4003-1783
Россия, Moscow; Moscow
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